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Multi-channel sperm quality analyzer

A sperm quality and analyzer technology, applied in the field of cell analysis, can solve problems such as errors, inability to automatically adjust the relative distance between the sample and the instrument, and low efficiency, so as to avoid detection errors, avoid high costs and high mechanical failures, and solve low-cost problems. effect

Inactive Publication Date: 2022-02-08
湖南星博智造生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the analyzer needs to replace the sample many times during the use process, and the relative distance between the sample and the instrument cannot be automatically adjusted, the efficiency is low, and it is easy to cause errors

Method used

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Experimental program
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Effect test

Embodiment 1

[0033] This embodiment provides a multi-channel sperm quality analyzer, combined with figure 1 , including a motion control system, an optical path system, a three-axis motion unit and a five-piece sample tray, the five-piece sample tray is used to place multiple sperm samples at the same time, and the three-axis motion unit is used to control the optical path system and The relative position between the five-piece sample trays, the optical path system is used to provide illumination channels and collect images, and the motion control system is used to drive the three-axis motion unit to move precisely;

[0034] The optical path system includes a bright-field lighting channel, a fluorescent lighting channel, an objective lens unit, an image acquisition system and an eyepiece unit. The bright-field lighting channel is located below the five-piece sample tray and provides ordinary light to improve the brightness of the sperm sample. The fluorescent lighting channel is located be...

Embodiment 2

[0051] This embodiment mainly consists of figure 1 The four parts shown are composed of a motion control system, an optical system, a three-axis motion unit, and a five-piece sample tray. Its main function is to analyze multiple indicators related to sperm quality. The analysis of this indicator previously required the cooperation of multiple sets of equipment. Complete detection and analysis, but with this invention, all the detection and analysis of the above indicators can be completed on one device. The main innovations of this invention are as follows:

[0052] In the past, the same type of equipment mostly used manual single-chip sample loading or cassette-type sample loading. This invention creatively uses a five-piece aluminum alloy detachable tray for sample loading. The motor drives itself according to the instructions, so that only a spare standard tray is prepared in advance, and the sample can be loaded and circulated in batches. This solution not only solves the ...

Embodiment 3

[0056] This embodiment includes all the content of the above-mentioned embodiments, and provides a multi-channel sperm quality analyzer, including a motion control system, an optical path system, a three-axis motion unit, and a five-piece sample tray. The five-piece sample tray is used for For placing the sperm sample, the optical path system is used to provide illumination and collect images of the sperm sample, the three-axis motion unit is used to control the relative position of the optical path system and the five-piece sample tray, and the motion control system used to control the motion of the three-axis motion unit and provide power for the motion of the three-axis motion unit;

[0057] The five-piece sample tray includes an interlayer, an x-axis motor and a tray, the tray is located inside the interlayer, and an opening is provided on the side of the interlayer, and the tray can be moved from the opening under the action of the x-axis motor. It is pushed out at the pl...

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Abstract

The invention provides a multi-channel sperm quality analyzer which comprises a motion control system, a light path system, a three-axis motion unit and a five-piece type sample wafer tray; the five-piece type sample wafer tray is used for placing a plurality of sperm sample wafers at the same time; the three-axis motion unit is used for controlling the relative position between the light path system and the five-piece sample tray; the light path system is used for providing an illumination channel and collecting images; and the motion control system is used for driving the three-axis motion unit to move accurately. According to the invention, multi-index analysis related to sperm quality can be realized, detection and analysis can be completed only by cooperation of a plurality of sets of equipment before analysis of the indexes, but all detection and analysis of the indexes can be completed on one set of equipment after the method is provided.

Description

technical field [0001] The present disclosure relates generally to the field of cell analysis, and more particularly to a multi-channel sperm quality analyzer. Background technique [0002] The earliest sperm detection room used multiple exposures to take pictures, and then recorded the trajectory of the sperm, and then calculated the movement characteristics of the sperm through projection and magnification. After the color image detection, the R&D personnel of Tsinghua University successfully launched the fluorescence image detection system. [0003] Now a lot of gold quality analyzers have been developed. After a large number of searches and references, we found that the existing analyzers are like the systems disclosed in KR101117318B1, KR101116034B1, CN101726578B and KR101777750B1, including sample input modules and microchannels; The measurement host includes a chip docking module, a fluid drive module, a signal detection and processing module, and a result display an...

Claims

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Application Information

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IPC IPC(8): G01N21/64G01N35/00
CPCG01N21/6458G01N35/00584
Inventor 黄亮李俊陈凯宏钱军张国勇
Owner 湖南星博智造生物科技有限公司
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