A kind of waterproof and breathable foam dressing and preparation method thereof

A waterproof, breathable, and foam technology, which is applied in medical science, absorbent pads, bandages, etc., can solve the problems of wound recovery that cannot be promoted, secondary injury of patients, skin hypoxia and whitening, etc., and achieves excellent biocompatibility Sexuality and adhesion, promote wound repair, prevent wound infection

Active Publication Date: 2022-07-12
河北卫崭医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional medical dressings are mainly made of natural materials such as cotton, gauze, and bandages. Most of them are dry and cannot actively provide a warm and moist healing environment for the wound. They cannot promote wound recovery and have limited ability to maintain cell tissue fluid. ; and the traditional medical dressing will be integrated with the tissue after the wound is healed, which will bring secondary injury and pain to the patient in the process of removing the dressing in the later stage
Therefore, traditional medical dressings have been difficult to meet people's needs, and new medical dressings with better performance are gradually attracting people's attention
[0004] However, the existing dressings also have the problems of poor air permeability and non-waterproofness. After a long time of use, the skin will turn white due to hypoxia, which is not conducive to wound repair, has poor moisture absorption effect, and is suitable for a single environment.

Method used

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  • A kind of waterproof and breathable foam dressing and preparation method thereof
  • A kind of waterproof and breathable foam dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] A method of manufacturing a waterproof and breathable foam dressing, comprising the steps of:

[0041] After mixing 20g of Panax notoginseng, 10g of Cork, 10g of dried blood, 10g of frankincense and 50g of deionized water, crushed after mixing, and filtered to obtain a filtrate with an impurity content of less than 0.1%;

[0042] After mixing 150 g of polyethylene glycol and 5 g of glycerin, heating to 60° C., adding 10 g of toluene diisocyanate, and stirring for 1 hour, the first reactant was obtained;

[0043] After mixing 50g of poloxamer, 5g of gentamicin and 20g of silicone oil L580, add 1g of polyvinylpyrrolidone and 114g of deionized water, and stir for 1min to obtain the second reactant;

[0044] Mix the first reactant and the second reactant in a weight ratio of 1:1, then add 1 g of carbomer, stir evenly at a speed of 1000 to 3000 r / min, then add 5 g of sodium hyaluronate and filtrate, and place it in the mixture. In the foaming mold, keep the temperature at 5...

Embodiment 2

[0047] A method of manufacturing a waterproof and breathable foam dressing, comprising the steps of:

[0048] After mixing 40g of Panax notoginseng, 20g of Cork, 15g of dried blood, 20g of frankincense and 142g of deionized water, the mixture was crushed, and then filtered to obtain a filtrate with an impurity content of less than 0.1%;

[0049] After mixing 160g polyethylene glycol and 12g glycerol, heating to 70°C, adding 20g toluene diisocyanate, and stirring for 1.5h, the first reactant was obtained;

[0050] After mixing 70g of poloxamer, 8g of gentamicin and 20g of silicone oil L580, add 3g of polyvinylpyrrolidone and 200g of deionized water, and stir for 1.5min to obtain the second reactant;

[0051] Mix the first reactant and the second reactant according to the weight ratio of 1.5:1, then add 3 g of carbomer, stir evenly at a speed of 1000 to 3000 r / min, then add 8 g of sodium hyaluronate and filtrate, and place it in the mixture. In the foaming mold, keep the temper...

Embodiment 3

[0054] A method of manufacturing a waterproof and breathable foam dressing, comprising the steps of:

[0055] After mixing 50g of Panax notoginseng, 30g of Cork, 20g of dried blood, 30g of frankincense and 260g of deionized water, crushed after mixing, and filtered to obtain a filtrate with an impurity content of less than 0.1%;

[0056] After mixing 170 g of polyethylene glycol and 20 g of glycerin, heating to 75° C., adding 30 g of toluene diisocyanate, and stirring for 2 hours, the first reactant was obtained;

[0057] After mixing 80g of poloxamer, 10g of gentamicin and 30g of silicone oil L580, add 5g of polyvinylpyrrolidone and 375g of deionized water, and stir for 2min to obtain the second reactant;

[0058] Mix the first reactant and the second reactant according to the weight ratio of 2:1, then add 5g of carbomer, stir evenly at a speed of 1000-3000r / min, then add 10g of sodium hyaluronate and filtrate, and place it in the mixture. In the foaming mold, keep the tempe...

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Abstract

The invention provides a waterproof and breathable foam dressing and a preparation method thereof, and relates to the technical field of medical dressings. A waterproof and breathable foam dressing, comprising the following raw materials by weight: 0.5-2 parts of glycerin, 0.1-0.5 parts of carbomers, 5-8 parts of poloxamers, 0.5-1 parts of antibiotics, and 2-3 parts of surfactants parts, 15-17 parts of polyethylene glycol, 1-3 parts of toluene diisocyanate, 0.1-0.5 parts of polyvinylpyrrolidone, 5-13 parts of auxiliary materials and 0.5-1 part of sodium hyaluronate. The preparation method includes obtaining a filtrate; obtaining a first reactant; obtaining a second reactant; obtaining a third reactant; and obtaining a finished product of a waterproof and breathable foam dressing. The waterproof and breathable foam dressing has the advantages of good air permeability, waterproof and good wound repairing effect.

Description

technical field [0001] The invention relates to the technical field of medical dressings, in particular to a waterproof and breathable foam dressing and a preparation method thereof. Background technique [0002] As the largest organ of the human body, the skin plays an important role in sensing external stimuli, regulating body temperature, regulating water evaporation loss, protecting various tissues and organs in the body from physical and chemical damage, and resisting the invasion of pathogenic microorganisms. When the skin is damaged in a large area, it will cause many local and even systemic problems, and even life-threatening in severe cases. Therefore, it is extremely important to cover the surface of the skin with medical dressings for repair in the case of large-area defects or difficult to heal. [0003] Medical dressings are medical hygienic materials used to temporarily cover the surface of various wounds and wounds. They can be used as a temporary substitute ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/42A61L15/46A61L15/28A61L15/20A61L15/26A61L15/24
Inventor 王亚海
Owner 河北卫崭医疗科技有限公司
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