Anti-inflammatory and blood fat-reducing composition, product and preparation method and application of anti-inflammatory and blood fat-reducing composition

A composition and blood lipid-lowering technology, applied in the direction of application, anti-inflammatory agents, drug combinations, etc., can solve problems such as impact, antibiotic resistance, etc.

Pending Publication Date: 2022-05-06
CHINA ACAD OF SCI NORTHWEST HIGHLAND BIOLOGY INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, there are many adverse reactions to antibiotics, which have adverse effects on the body, and while antibiotics have anti-inflammatory effects, they can also cause bacteria to develop resistance to antibiotics imperceptibly

Method used

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  • Anti-inflammatory and blood fat-reducing composition, product and preparation method and application of anti-inflammatory and blood fat-reducing composition
  • Anti-inflammatory and blood fat-reducing composition, product and preparation method and application of anti-inflammatory and blood fat-reducing composition
  • Anti-inflammatory and blood fat-reducing composition, product and preparation method and application of anti-inflammatory and blood fat-reducing composition

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preparation example Construction

[0028] The present invention provides the preparation method of above-mentioned composition, described method comprises the steps:

[0029] The fruit of sugar currant, stems and leaves of sugar currant, mulberry leaves and lotus leaves are mixed for pulverization and water extraction, and the obtained extract is filtered through a membrane, and the filtrate with a molecular interception of 150D is removed by an ultrafiltration membrane. After the filtrate is dried, the extract A comprising sugar currant fruit extract, sugar currant stem and leaf extract, mulberry leaf extract and lotus leaf extract is obtained; the extract A is mixed with oat β-glucan and chitosan oligosaccharide are mixed to obtain the composition.

[0030] In the present invention, the crushed particle size is preferably 15-25 mesh, more preferably 20 mesh. The temperature of the water extraction is preferably 42-58°C, more preferably 50°C. The solid-liquid ratio of the water extraction is preferably 1g:15...

Embodiment 1

[0038] (1) mix 500 g of sugar currant fruit, 500 g of sugar currant stem and leaf, 200 g of mulberry leaves, and 200 g of lotus leaves, and coarsely crush it to a particle size of 20 mesh;

[0039] (2) adding water to extract the pulverized mixture in step (1), the ratio of solid to liquid is 1g:20mL, the extraction temperature is 50°C, and extracted 3 times;

[0040] (3) The solution after step (2) water leaching is micro-filtered through a 0.2 μm ceramic membrane membrane;

[0041] (4) The solution after microfiltration adopts polyethersulfone ultrafiltration membrane to remove impurities, and the molecular weight cut-off is a component of 10000D;

[0042] (5) The components intercepted in step (4) continue to be concentrated by nanofiltration membranes, and the components with a molecular weight cut-off of 150D are vacuum-dried to obtain sugar-cured fruit, sugar-currant stems and leaves, mulberry leaves, and lotus leaves. Extract A made from leaves;

[0043] (6) Mix the e...

Embodiment 2

[0045] (1) Mix 600 g of sugar-cured fruit, 600 g of sugar-currant stem and leaf, 300 g of mulberry leaves, and 300 g of lotus leaves, and coarsely crush them to a particle size of 15 mesh;

[0046] (2) adding water to extract the pulverized mixture in step (1), the ratio of solid to liquid is 1g:20mL, the extraction temperature is 42°C, and extracted 3 times;

[0047] (3) The solution after step (2) water leaching is micro-filtered through a 0.2 μm ceramic membrane membrane;

[0048] (4) The solution after microfiltration adopts polyethersulfone ultrafiltration membrane to remove impurities, and the molecular weight cut-off is a component of 10000D;

[0049] (5) The components intercepted in step (4) continue to be concentrated by nanofiltration membranes, and the components with a molecular weight cut-off of 150D are vacuum-dried to obtain sugar-cured fruit, sugar-currant stems and leaves, mulberry leaves, and lotus leaves. Extract A made from leaves;

[0050] (6) Mix the ext...

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Abstract

The invention relates to an anti-inflammatory and blood fat reducing composition, a product and a preparation method and application thereof, and belongs to the technical field of functional food. The invention provides an anti-inflammatory and blood fat-reducing traditional Chinese medicine composition which comprises a sugared Ribes nigrum fruit extract, a sugared Ribes nigrum stem and leaf extract, a mulberry leaf extract, a lotus leaf extract, oat beta-glucan and chitosan oligosaccharide, and the composition takes total flavonoids as an active ingredient and also contains effective ingredients such as tea polyphenol. Experiments prove that the composition disclosed by the invention has a synergistic effect and has good anti-inflammatory and blood fat reducing effects. Meanwhile, the raw materials of the composition are all medicinal and edible materials, so that the composition can be eaten for a long time, has no toxic or side effect and has a very good application prospect.

Description

technical field [0001] The invention relates to the technical field of functional food, in particular to an anti-inflammation and hypolipidemic composition, product, preparation method and application thereof. Background technique [0002] Inflammation is caused by bacteria or fungi invading the human body. At present, antibiotics are mainly used clinically to treat inflammatory diseases caused by bacteria. However, there are many adverse reactions to antibiotics, which have adverse effects on the body, and while antibiotics have anti-inflammatory effects, they can also cause bacteria to develop resistance to antibiotics imperceptibly. [0003] The total number of people with dyslipidemia in my country has exceeded 160 million, and the number of these patients is still increasing. It is worth our attention that millions of patients with coronary heart disease and fatty liver need lipid-lowering therapy. According to the relevant statistical data of medical diseases, the de...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/62A61P3/06A61P29/00A23L33/105A23L33/125A61K31/702A61K31/716
CPCA61K36/185A61K36/605A61K36/62A61K31/716A61K31/702A61P3/06A61P29/00A23L33/105A23L33/125A23V2002/00A61K2300/00A23V2200/30A23V2200/3262A23V2250/21A23V2250/5034A23V2250/28
Inventor 邵贇党军刘闯刘增根岳会兰文怀秀
Owner CHINA ACAD OF SCI NORTHWEST HIGHLAND BIOLOGY INST
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