Compound buckwheat flower and leaf flavones preparation for controlling diabetes and complicating disease thereof and preparation method thereof

A technology of compound buckwheat leaf flavonoids and complications, which is applied in the field of prevention and treatment of diabetes and complications medicines and its preparation, can solve the problems of limited selection, large dosage, inconvenient application, etc. and high-purity, easy-to-apply effects

Inactive Publication Date: 2009-04-29
韩淑英 +8
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the selection of clinical Chinese medicines is limited, and there are only dozens of commonly used ones. At the same time, most of the traditional Chinese medicines used in clinical applications have disadvantages such as large doses, inconvenient application, and relatively expensive prices.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] (percentage by weight) buckwheat flavonoids: 10%, Pueraria radix and other traditional Chinese medicine extracts: 90%, and the proportions of crude drugs in Pueraria radiata and other traditional Chinese medicine extracts are: Pueraria 25%, Trichosanthes 15%, Ophiopogon japonicus 25%, Scrophulariaceae 15%, Hemp seed 20%.

Embodiment 2

[0030] (percentage by weight) buckwheat flavonoids: 15%, Pueraria radix and other traditional Chinese medicine extracts: 85%, and the proportions of crude drugs in Pueraria radiata and other traditional Chinese medicine extracts are: Pueraria 15%, Trichosanthes 25%, Ophiopogon japonicus 25%, Scrophulariaceae 15%, Hemp seed 20%.

Embodiment 3

[0032] (percentage by weight) buckwheat flavonoids: 20%, Pueraria radix and other traditional Chinese medicine extracts: 80%, and the proportions of crude drugs in Pueraria radiata and other traditional Chinese medicine extracts are: Pueraria 25%, Trichosanthes 25%, Ophiopogon japonicus 15%, Scrophulariaceae 20%, Hemp seed 15%.

[0033] The preparation process of each embodiment is as follows:

[0034] ①Preparation of flavonoids from buckwheat mosaic leaves: buckwheat mosaic leaves are the natural dried product of sweet buckwheat (grain crop buckwheat, buckwheat) mosaic leaves of Polygonaceae plant, which are rich in flavonoids. The extraction process of the flavonoids is as follows:

[0035] Buckwheat flowers and leaves were heated and refluxed twice with deionized water, each time for 1 hour, the filtrates were combined twice, concentrated to 1 / 4-1 / 5 of the original liquid, and a separating agent was added to adjust the pH to 4-6, 70- Heat and stir at 80°C for 30 minutes, a...

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PUM

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Abstract

The invention relates to a drug for preventing and curing diabetes and complicating diseases and a preparation method thereof, in particular to a compound buckwheat flower leaf flavones preparation for preventing and curing diabetes and complicating diseases and a preparation method thereof. The technical proposal is that: the drug contains buckwheat flavones and other extracts from Chinese traditional drugs which comprise kudzu root, root of Chinese trichosannthes, dwarf lilyturf root, scrophulariaceae canaria and edestan; the weight percentage between the buckwheat flavones and the other extracts from Chinese traditional drugs is: 10 percent to 20 percent of the buckwheat flavones and 80 percent to 90 percent of the other extracts from Chinese traditional drugs, wherein, the weight percentage of every crude drug in the other extracts from Chinese traditional drugs is: 15 percent to 25 percent of kudzu root, 15 percent to 25 percent of root of Chinese trichosannthes, 15 percent to 25 percent of dwarf lilyturf root, 10 percent to 20 percent of scrophulariaceae canaria and 10 percent to 20 percent of edestan. The drug is applied to the cure of animal model of diabetes, showing obvious functions of blood sugar and blood fat reduction, improvement of the insulin resistance and reduction of such symptoms of diabetes as more blood sugar, more blood fat, more blood plasma and less insulin. The drug has obvious advantages of the reduction and delay of the occurrence and development of complicating diseases of diabetes, showing that the compound buckwheat flower leaf flavones preparation has great prevention and cure effects on the diabetes and the complicating diseases thereof.

Description

Technical field: [0001] The invention relates to a medicine for preventing and treating diabetes and complications and a preparation method thereof, in particular to a compound buckwheat leaf flavonoid preparation for preventing and treating diabetes and complications and a preparation method thereof. Background technique: [0002] Diabetes has become one of the three major diseases in the world. With the improvement of people's living standards, the incidence of population aging, diabetes and obesity is increasing year by year, especially the incidence of type 2 diabetes is higher, which has become a chronic disease that seriously threatens human health. . Diabetes is not only a high incidence rate, but more importantly, it is a complication caused by diabetes. With the prolongation of the course of diabetes, it can lead to blindness, cardiovascular and cerebrovascular diseases, liver function damage, renal failure, neuropathy, limb gangrene and even amputation, coma and o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61K36/70A61P3/10A61K127/00A61K133/00
Inventor 韩淑英马会霞包巨太朱丽莎王志路赵刃储金秀余红吴范武
Owner 韩淑英
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