Unlock instant, AI-driven research and patent intelligence for your innovation.

Huoxiang Zhengqi liquid capsule and its preparation

A Huoxiang Zhengqi, liquid technology, applied in the direction of capsule delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of prolonged disintegration time of soft capsules, poor taste, low content of volatile components, etc., to reduce The effect of disintegration time

Inactive Publication Date: 2006-06-14
津药达仁堂集团股份有限公司达仁堂制药厂
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because more than 60% of the medicinal taste of this prescription contains volatile components and plays a major role in the prescription, and the above-mentioned alcohol-containing water (Huoxiangzhengqi water) can completely dissolve the volatile components with ethanol, and the curative effect is better, but due to poor taste , the high alcohol content stimulates the stomach and is not easily accepted by women and children: other dosage forms have low curative effect due to the low content of volatile components: the soft capsule dosage form can wrap the volatile oil-soluble components in the capsule shell, which is a traditional Chinese medicine preparation A revolution in the industry, but soft capsules are troubled by the prolongation of disintegration time with storage time

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] According to the records in the preparation of Huoxiangzhengqi Soft Capsules on page 16 of the fifth volume of the new drug standard, prepare atractylodes rhizome, tangerine peel, magnolia officinalis (made from ginger), Angelica dahurica, Poria cocos, Dabupi, raw pinellia, licorice extract, and patchouli oil , perilla leaf oil, dried ginger and eleven medicinal materials, wherein Zizhi, tangerine peel, atractylodes rhizome, and Magnolia officinalis are extracted twice with 90-95% ethanol under reflux (3 hours for the first time, 2 hours for the second time), and the filtrates are combined. Concentrate under reduced pressure into a paste (relative density 1.18-1.20) to obtain Siwei paste for later use; soak the raw pinellia in cold water, change the water every 8 hours, change the water twice, soak until the heart is penetrated, take pinellia, and add Dried ginger 16.46g, decoct twice with water (3 hours for the first time, 2 hours for the second time); boil Poria cocos ...

Embodiment 2

[0028] According to the records in the preparation of Huoxiangzhengqi Soft Capsules on page 16 of the fifth volume of the new drug standard, prepare atractylodes rhizome, tangerine peel, magnolia officinalis (made from ginger), Angelica dahurica, Poria cocos, Dabupi, raw pinellia, licorice extract, and patchouli oil , perilla leaf oil, dried ginger eleven medicinal materials, wherein Angelica dahurica, dried tangerine peel, atractylodes atractylodes, Magnolia officinalis extract twice with 90-95% ethanol reflux (first time 3 hours, second time 2 hours), filtrate merges, reduces Press and condense into a paste (relative density 1.18-1.20) to obtain Siwei paste for later use; soak the raw pinellia in cold water, change the water every 8 hours, change the water twice, soak until the heart is clear, take the pinellia, and dry it again Ginger 16.46g, decoct twice with water (3 hours for the first time, 2 hours for the second time); boil Poria cocos and Dabupi for 2 times (1 hour for...

Embodiment 3

[0030] Prescription 1

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a high-efficiency, quick-acting and stable-acting Huoxiangzhengqi liquid capsule, which is prepared by filling the emulsion of Huoxiangzhengqi preparation prepared by proportioning various components into a hard gelatin capsule. The Huoxiangzhengqi capsule preparation has high content of volatile medicinal components and quick onset of action.

Description

technical field [0001] The invention relates to a Huoxiang Zhengqi capsule, more specifically, a Huoxiang Zhengqi liquid capsule; the invention also relates to a preparation method of the liquid capsule. Background technique [0002] Huoxiangzhengqi Soft Capsules originated from the "Taiping Huimin Heji Bureau Prescription" in the Song Dynasty. It has been honored as the "Holy Medicine for Dispelling Dampness" by physicians of all dynasties. It is used for diseases such as exogenous wind and cold, internal injury and stagnation of dampness, headache, dizziness, abdominal pain, vomiting and diarrhea. It is a must-have medicine in summer. Because Huoxiangzhengqi has the advantages in treatment, it is widely used, and it has become a variety with the most dosage forms in my country, including honey pills, water pills, concentrated pills, tablets, granules, oral liquids, alcohol-containing water preparations, soft capsules, Hard capsules and other...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/66A61K36/9068A61K125/00A61K36/889A61K131/00A61K36/8888A61K36/752A61K36/575A61K129/00A61K36/535A61K127/00A61K135/00A61P1/14A61P1/12A61P1/08A61P31/00A61K9/48
Inventor 徐晓阳金兆祥
Owner 津药达仁堂集团股份有限公司达仁堂制药厂