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Levo carnitine dropping pill and preparation thereof

A technology of L-carnitine and dripping pills, which is applied in pill delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems that there is no public technical information of L-carnitine dripping pills, and avoid the first-pass effect of liver and intestines , the total surface area increases, the effect of rapid onset

Active Publication Date: 2007-06-27
JIANGXI JIMINKEXIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

According to the investigation, there is no public technical information or report about L-carnitine dripping pills

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0040] Now with several groups of specific examples, the preparation method of L-carnitine dripping pills of the present invention will be further described.

[0041] [The first group: L-carnitine dripping pills prepared with L-carnitine as the active ingredient]

[0042] 1. The embodiment using a single matrix

[0043] 1.1 English name of L-carnitine - L-carnitine, Chinese translation - Kang Liting;

[0044] Alias ​​- L-carnitine, vitamin B T ;

[0045] Chemical name - the chemical name is L-β-hydroxy-γ-methylammonium butyric acid;

[0046] 1.2 Substrate - polyethylene glycol (2000～20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac;

[0047] 1.3 Ratio - in g or kg, L-carnitine: matrix = 1:1 ~ 1:5;

[0048] 1.4 According to the steps of [Preparation Method] 4-7, L-carnitine dripping pills of different specifications can be prepared.

[0049] [test resul...

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PUM

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Abstract

The invention relates to levo carnitine dropping pill for treating adiposis, hepatic disease, which has a high bioavailability, a fast medicine release, a small toxic and deleterious effect, a low utilized cost, and no pollution. The levo carnitine dropping pill takes the levo carnitine or the tartrate and fumarate as medicine active component and can be prepared together with the medicinal carrier as substrate.

Description

technical field [0001] The invention relates to a medicine for treating obesity and liver disease, in particular to an oral preparation of a pharmaceutical composition which takes L-carnitine (or its salts) as an active pharmaceutical ingredient and has the functions of reducing weight and inhibiting liver disease. Background technique [0002] At present, with the improvement of people's living standards in our country, the incidence of obesity is gradually increasing. In 1982, 1989 and 1992, the incidence of overweight and obesity in cities across the country was 9.7%, 12.0% and 14.9%, showing a gradual increase. rising trend. Obesity itself and its closely concurrent hypertension, dyslipidemia, type II diabetes, coronary heart disease and some tumors have seriously affected people's quality of life and shortened their lifespan. It is currently recognized that a 5% to 10% reduction in body weight can significantly improve the above risk factors associated with obesity, an...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/205A61K9/20A61P3/04A61P1/16
Inventor 曲韵智
Owner JIANGXI JIMINKEXIN PHARMA
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