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Chinese medicinal composition for treating rheumatoid arthritis

A composition and technology for arthritis, applied in the direction of drug combinations, antipyretics, anti-inflammatory agents, etc., can solve the problems of patients' economic losses, high prices, and intolerance to discontinue use halfway

Inactive Publication Date: 2004-12-15
SHANDONG UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, in the treatment of modern medicine, drugs occupy the primary position, mainly including non-steroidal anti-inflammatory drugs, slow-acting anti-rheumatic drugs, immunosuppressants, glucocorticoids, etc., whether the treatment mode is a pyramid, a modified pyramid mode, or a sawtooth mode. , step-up or step-down mode, or combination of drugs, there is no definite curative effect
And long-term use of these drugs in large quantities will cause side effects of varying degrees, and some patients cannot tolerate midway discontinuation, and these drugs are relatively expensive, causing huge economic losses to patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0121] Accurately weigh the following raw materials: 360g of honeysuckle, 285g of Qingfengteng, 250g of Radix Paeoniae Alba, 178g of Fritillaria, 54g of Dried Ginger, 250g of Sacred Root, 250g of Radix Isatidis, and 250g of Achyranthes Radix.

[0122] Honeysuckle and Chuan Achyranthes bidentata were extracted three times with water (8, 6, and 4 times the amount of water added), each time for 1 hour, the water extracts were combined, filtered, concentrated under reduced pressure, dried, and crushed through a 40-mesh sieve.

[0123] Combine Qingfengteng and Tubeimu, add 16 times the amount of 70% ethanol, extract twice (1.5h, 1.5h), combine the ethanol extracts, recover ethanol under reduced pressure and concentrate to the specified concentration, dry under reduced pressure, and pulverize Pass through a 40 mesh sieve.

[0124] Combine Radix Paeoniae Alba, Sacred Teng and Radix Isatidis, add 16 times the amount of water, extract 3 times (1.5h, 1.5h, 1.5h), combine the water extra...

Embodiment 2

[0129] Accurately weigh the following raw materials: honeysuckle 380g, Qingfengteng 230g, white peony root 300g, soil fritillary 160g, dried ginger 80g, Daxueteng 220g, Radix isatidis 280g, Chuan Achyranthes bidentata 250g.

[0130] Mix the above dry extract and cyclodextrin inclusion compound evenly, add 2% magnesium stearate, mix, pack into capsules, and make 1000 capsules, 0.55g / capsule.

[0131] Usage and dosage: Take orally, three times a day, 4 capsules / time.

Embodiment 3

[0133] Accurately weigh the following raw materials: honeysuckle 310g, Qingfengteng 280g, white peony root 200g, soil fritillary 200g, dried ginger 35g, Daxueteng 290g, Radix Radix 220g, and Achyranthes bidentata 290g.

[0134] The preparation method is the same as in Example 1. Obtained extract 480g. Add appropriate amount of microcrystalline cellulose and press into tablets. 0.5g / tablet.

[0135] Usage and dosage: Take orally, three times a day, 4 tablets / time.

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Abstract

The Chinese medicine composition is prepared with eight kinds of Chinese medicinal materials including honeysuckle, orietvine stem, white peony root, paniculate bolbostemma rhizome, dry ginger, etc. as well as medicinal supplementary material. The Chinese medicine composition has the advantages of high curative effect on rheumatoid arthritis, no toxic side effect, low cost, convenient taking and no recurrence.

Description

(1) Technical field [0001] The invention belongs to a medicine for treating rheumatoid diseases, in particular to a pure traditional Chinese medicine preparation for treating rheumatoid diseases. (2) Background technology [0002] Rheumatoid arthritis is a heterogeneous and systemic disease with symmetric polyarthritis as the main clinical manifestation, and its etiology is still unclear. At present, it is mostly believed that the occurrence of the disease is related to factors such as infection, immune disorders, hormones and the environment. The disease is a chronic, progressive, aggressive disease. If proper treatment is not given during the active phase, the disease will gradually develop and aggravate. Finally, it leads to different degrees of disability such as joint ankylosis, deformity, and loss of function. At present, in the treatment of modern medicine, drugs occupy the primary position, mainly including non-steroidal anti-inflammatory drugs, slow-acting anti-rh...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61K9/48A61P19/02A61P29/00
Inventor 张鸣鹤宋绍亮
Owner SHANDONG UNIV OF TRADITIONAL CHINESE MEDICINE
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