Non-toxic ionic liquid, preparation method and its application

An ionic liquid and anion technology, applied in pharmaceutical formulations, medical preparations with non-active ingredients, etc., can solve the problems of complex preparation process, toxicity, side effects on human body, etc., and achieve simple preparation process, good solubilization and solubilization, Wide range of effects in the liquid phase
CN1651089AInactive Publication Date: 2005-08-10HEBEI NORMAL UNIV
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
HEBEI NORMAL UNIV
Publication Date
2005-08-10
Estimated Expiration
Not applicable · inactive patent

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Abstract

A non-toxic ionic liquid used as the solvent, cosolvent, or surfactant for increasing the water-solubility of the medicines difficult to dissolve in water features that its cation is alkylimidazole salt with short carbon chain or quaternary ammonium salt.
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Description

technical field

[0001] The invention belongs to the synthesis of new ionic liquid in the field of chemical materials and its manufacture and the application in the field of medicine as a new solvent, co-solvent or surfactant. Background technique

[0002] Ionic Liquids (Ionic Liquids) refer to positive ions such as organic alkylimidazoles, quaternary ammonium salts, and alkylpyridines and different negative ions such as chloride ions, BF 4 - , PF 6 - , CF 3 CO 2 - , N(CN) - 2 Many of them are liquid at room temperature or even at low temperature, so they are also called room temperature ionic liquids. Ionic liquids have the characteristics of no vapor pressure, good thermal stability (up to 300-400°C), good electrical conductivity, and are suitable for organic compounds, inorganic compounds, metal organic compounds, gases (H 2 , CO, O 2 etc.) have a wide range of solubility, can be miscible or insoluble with organic solvents, water to form a two-phase or multi-phas...

Claims

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