Fritillaria flower drip pill and its preparation method

A technology of fritillary flower and flower drop pills, which can be applied in the fields of pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc., which can solve problems that are not conducive to improving patients' ability to seek medical treatment, bioavailability of the first-pass effect of the liver and intestines, and adverse overall health Level and other issues, to achieve the effect of benefiting labor protection and environmental protection, improving bioavailability, and drug safety

Inactive Publication Date: 2005-10-26
北京博智绿洲医药科技有限公司
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AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
In addition, conventional oral dosage forms, such as tablets, capsules, granules (infusions), etc., due to the granulation process in the preparation process, will generate relatively large dust pollution, which will cause health problems to the staff to a certain extent. harm, and also cause some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
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Embodiment Construction

[0027] Now with several groups of specific examples, the preparation method of Fritillary Flower Dropping Pills of the present invention will be further described.

[0028] [Group 1: Trials with a single substrate]

[0029] 1. Raw materials: According to [Preparation Method 1], the dry powder of the extract containing the active pharmaceutical ingredients of the traditional Chinese medicine Fritillaria is prepared for later use;

[0030] 2. Substrate: polyethylene glycol 1000 , polyethylene glycol 4000 , polyethylene glycol 6000 , polyethylene glycol 10000 , polyethylene glycol 20000 , Span 40, polyoxyl 40 stearate, poloxamer, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac;

[0031] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0032] 4. Prepare according to the process given in [Preparation Method] 4-7 ​​to obtain Fritillary Flower Dropping Pills of different specifications.

[0033] [test results...

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PUM

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Abstract

A Chinese medicine in the form of dripping pill for treating cough with sputum, bronchitis, etc is prepared from tendrilled fritillary flower and medicinal carrier. Its preparing process is also disclosed.

Description

technical field [0001] The present invention relates to a kind of medicine composition that has cough-relieving and phlegm-resolving effects, and is used for the treatment of diseases such as cough and phlegm, bronchitis, etc., and particularly relates to an oral preparation of a kind of medicine composition prepared by taking Chinese medicinal material Fritillaria chinensis as a raw material. Background technique [0002] According to the preparation method given in the national drug standard WS-10874 (ZD-0874)-2002, the fritillary flower tablet is a kind of cough-relieving and phlegm-reducing effect, which is used for the treatment of cough, phlegm, bronchitis and other diseases. The oral tablet of the product has been clinically verified and has definite curative effect. It is a commonly used drug for clinical and family use to treat the above diseases. [0003] The following is the formula, process and brief description given in the pharmaceutical standard WS-10874 (ZD-0...

Claims

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Application Information

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Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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