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Cefadole oral liquor antibacterial composition

An antibacterial composition, cefaclor technology, applied in the direction of antibacterial drugs, active ingredients of heterocyclic compounds, organic active ingredients, etc., can solve the problem of antibacterial effect decline, and achieve good antibacterial and bactericidal effects in vitro

Inactive Publication Date: 2006-03-08
HAINAN JINXING PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] With the widespread clinical application of cefaclor, some sensitive strains have developed resistance to cefaclor, making its antibacterial effect decline

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] The cefaclor oral antibacterial composition is composed of cefaclor and sulbactam pivoxil, and the weight ratio of cefaclor and sulbactam pivoxil is 1:1.

Embodiment 2

[0014] The cefaclor oral antibacterial composition is composed of cefaclor and sulbactam pivoxil, and the weight ratio of cefaclor and sulbactam pivoxil is 2:1.

Embodiment 3

[0016] The cefaclor oral antibacterial composition is composed of cefaclor and sulbactam pivoxil, and the weight ratio of cefaclor and sulbactam pivoxil is 4:1.

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PUM

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Abstract

The present invention discloses an oral antimicrobial medicine composite composed of cefaclor and sulbactam pivoxil. The weight ratio range of cefaclor and sulbactam pivoxil in said oral antimicrobial medicine composite is 1:1 to 15:1, and the optimized weight ratio range is 1:1 to 6:1.

Description

technical field [0001] The invention relates to a compound antibacterial drug, which is an anti-beta-lactamase antibiotic oral antibacterial composition. Background technique [0002] Cefaclor (Cefaclor) is a first-generation cephalosporin, a semi-synthetic β-lactam broad-spectrum antibiotic. Its antibacterial properties: In addition to Enterococcus, it has strong antibacterial activity against other Gram-positive cocci and common Gram-negative bacilli, and has strong antibacterial activity against penicillin-resistant Staphylococcus aureus and Haemophilus influenzae. Antibacterial spectrum: Staphylococcus aureus, Staphylococcus epidermidis (including penicillinase-producing and non-methicillin-resistant strains), Streptococcus pneumoniae, Diphtheria, Klebsiella, Clostridium, Escherichia coli, Proteus mirabilis, Haemophilus influenzae, Neisseria gonorrhoeae, Pneumococcus, Salmonella, Shigella, Meningococcus, etc. are sensitive to this product. Enterococcus faecalis, Entero...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/545A61P31/04A61K31/43
Inventor 刘全胜夏中宁舒军林学良
Owner HAINAN JINXING PHARMA
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