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Shenfu freeze driet powder injection and its preparation method

A technology of freeze-dried powder injection and attached tablet, which is applied in the field of medicine, can solve the problems of unsatisfactory solubility of Shenfu freeze-dried powder injection, etc., and achieve the effects of increasing survival time and survival rate, slowing heart rate, and stable quality.

Inactive Publication Date: 2006-06-14
沈阳斯佳科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Chinese patent, application number 03135699.0 discloses a preparation method of Shenfu freeze-dried powder injection, but the solubility of Shenfu freeze-dried powder injection prepared by this method is not ideal enough

Method used

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  • Shenfu freeze driet powder injection and its preparation method
  • Shenfu freeze driet powder injection and its preparation method
  • Shenfu freeze driet powder injection and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0101] 1000 prescriptions: 1000g red ginseng, 2000g attached tablets, 250g mannitol, add water for injection to a total volume of 5000ml.

[0102] The preparation method comprises the following process steps:

[0103] Take 1000g of red ginseng herbs and crush them into coarse powder, add 6000ml of 75% ethanol to soak for 12 hours, filter, add 6000ml of 75% ethanol to the dregs and extract ultrasonically (power 100W, temperature 30°C) 3 times, each time for 20 minutes, combine the extracts, Filtrate, merge with soaking filtrate, recover ethanol under reduced pressure, and elute through macroporous resin, the type of macroporous resin is D101 type, and the ratio of resin diameter to height is 1:10, first elute with water, 20% ethanol, discard Remove water and 20% ethanol eluate, collect 30%, 50%, and 70% ethanol eluate (the amount of each elution solvent is equivalent to 3 times the volume of the column), recover the solvent under reduced pressure until there is no alcohol smell...

Embodiment 2

[0107] 1000 prescriptions: 1000g red ginseng, 2000g attached tablets, 200g mannitol, add water for injection to a total volume of 5000ml.

[0108] The preparation method comprises the following process steps:

[0109] Take 1000g of red ginseng medicinal materials and crush them into coarse powder, add 4000ml of 75% ethanol to soak for 12 hours, filter, add 8000ml of 75% ethanol to the dregs and ultrasonically extract (power 100W, temperature 30°C) 3 times, each time for 20 minutes, combine the extracts, Filtrate, combine with soaked filtrate, recover ethanol under reduced pressure, elute with macroporous resin, first elute with water and 20% ethanol, discard water and 20% ethanol eluate, collect 30%, 50%, 70% ethanol eluent (the amount of each elution solvent is equivalent to 3 times the volume of the macroporous resin column), the solvent is recovered under reduced pressure until there is no alcohol smell, and dried to obtain the red ginseng extract, which is set aside;

[0...

Embodiment 3

[0113] 1000 prescriptions: 1000g red ginseng, 2000g attached tablets, 300g mannitol, add water for injection to a total volume of 5000ml.

[0114] Its preparation method comprises the following steps:

[0115] Take red ginseng and grind it into coarse powder, add 6 times the amount of 75% ethanol to soak for 12 hours, filter, add 6 times the amount of 75% ethanol to ultrasonic extraction (power 100W, temperature 30°C) 3 times, each time for 20 minutes, combine The extract is filtered, combined with the soaked filtrate, the ethanol is recovered under reduced pressure, eluted with a macroporous resin, the solvent is recovered under reduced pressure until there is no alcohol smell, dried to obtain the red ginseng extract, and set aside;

[0116] Take Heifu Tablets and crush them into coarse powder, soak them in 6 times the amount of 75% ethanol for 12 hours, filter, add 6 times the amount of 75% ethanol to the filter residue and ultrasonically extract 3 times (power 100W, tempera...

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PUM

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Abstract

A Chinese medicine in the form of freeze-dried powder injection for restoring Yang from collapse, replanishing Qi, and treating Qi obstruction of chest is proportionally prepared from red ginseng, sliced and prepared aconite root and mannitol. Its preparing process is also disclosed.

Description

Technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a Shenfu freeze-dried powder injection and a preparation method thereof. Background technique [0002] Ginseng for injection is derived from the ancient prescription Ginseng Decoction. The ancients took ginseng to invigorate vital energy, solidify and promote body fluid, and Fu tablets can warm and strengthen the true yang and promote yang luck. Gutuo effect, clinically can be used to treat Juetuo syndrome (shock) caused by Yang Qi deficiency; according to the pharmacological effects of ginseng and Fupian, the ancients also used it to treat other clinical diseases caused by Yang Qi deficiency. Such as chest obstruction and convulsions caused by deficiency of heart yang qi; wheezing and coughing due to deficiency of lung and kidney yang; stomach pain and diarrhea due to deficiency of spleen and stomach yang; edema and impotence due to deficiency of kidney yang; Lumba...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61K9/19A61P1/14
Inventor 王光李莉马红萍
Owner 沈阳斯佳科技发展有限公司
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