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Compound Chinese medicine for anticancer and its preparation method

A traditional Chinese medicine preparation and technology of traditional Chinese medicine, applied in the direction of anti-tumor drugs, pharmaceutical formulations, drug delivery, etc., can solve the problems of treating the symptoms but not the root cause, using expensive ingredients, and inaccurate curative effects.

Inactive Publication Date: 2006-06-14
FUKANGREN BIO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In recent years, with the deepening of clinical research, some traditional Chinese medicines for the treatment of malignant tumors have also appeared on the market, but some of the existing medicines treat the symptoms but not the root cause, some use expensive ingredients, and some are discontinued due to inaccurate curative effects during the application process

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] It is characterized in that it contains four kinds of traditional Chinese medicines: astragalus, Brucea javanica, curcuma and coix seed. (Prescription①)

[0067] The preparation method of the active ingredient of Radix Astragali is as follows: take 3000g of Radix Astragali medicinal material, add water and decoct three times, the amount of water added each time is 10 times, 8 times, and 8 times respectively, the extract is centrifuged through a tubular centrifuge, and the centrifuged liquid is passed through D 101 Adsorption by macroporous resin, collect the effluent, and store in another container; wash the macroporous resin with water until the effluent is light-colored, then elute with 75% ethanol, collect the eluate, concentrate under reduced pressure, spray dry, use 90% ethanol for dry powder Reflux extraction, recovery of ethanol from the extract, concentration into a paste, and drying to obtain 61.2 g of the active ingredient of Radix Astragali. Take the macropo...

Embodiment 2

[0079] It is characterized in that it contains five kinds of traditional Chinese medicines: astragalus, Brucea javanica, curcuma, coix seed and mylabris. (prescription ②)

[0080] The preparation of the injection is as follows:

[0081] The preparation method of the active ingredient of Radix Astragali is as follows: take 3000g of Radix Astragali medicinal material, add water and decoct three times, the amount of water added each time is 10 times, 8 times, and 8 times respectively, the extract is centrifuged through a tubular centrifuge, and the centrifuged liquid is passed through D 101 Adsorption by macroporous resin, collect the effluent, and store in another container; wash the macroporous resin with water until the effluent is light-colored, then elute with 75% ethanol, collect the eluate, concentrate under reduced pressure, spray dry, use 90% ethanol for dry powder Reflux extraction, recovery of ethanol from the extract, concentration into a paste, and drying to obtain ...

Embodiment 3

[0095] It is characterized in that it contains five kinds of traditional Chinese medicines: Astragalus, Brucea Brucea, Curcuma, Coix Seed and Toad. (prescription ③)

[0096] The preparation of the injection is as follows:

[0097] The preparation method of the active ingredient of Radix Astragali is as follows: take 3000g of Radix Astragali medicinal material, add water and decoct three times, the amount of water added each time is 10 times, 8 times, and 8 times respectively, the extract is centrifuged through a tubular centrifuge, and the centrifuged liquid is passed through D 101 Adsorption by macroporous resin, collect the effluent, and store in another container; wash the macroporous resin with water until the effluent is light-colored, then elute with 75% ethanol, collect the eluate, concentrate under reduced pressure, spray dry, use 90% ethanol for dry powder Reflux extraction, recovery of ethanol from the extract, concentration into a paste, and drying to obtain 59.6 g...

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Abstract

An anticancer Chinese medicine in the form of injection, dripping pill and capsule is prepared from astragalus root, brucea fruit, zedoary oil, coix seed, and optional others. Its preparing process is also disclosed.

Description

Technical field: [0001] The invention relates to an anticancer traditional Chinese medicine compound preparation and a preparation method, which is characterized in that the compound preparation is made of traditional Chinese medicine raw materials astragalus, brucea javanica, curcuma oil and coix seed, and other traditional Chinese medicines can be added to the preparation to adjust its effect as required. Background technique: [0002] According to the research of the National Cancer Prevention and Research Office on the death trend of malignant tumors in my country in the past 20 years, the adjusted mortality rate of malignant tumors in my country was 84.58 / 100,000 in the 1970s and 94.36 / 100,000 in the 1990s, an increase of 11.56%. The main malignant tumors that have risen are: gastric cancer (9.95%), liver cancer (41.17%), lung cancer (111.85%) and leukemia (30.26%), which pose a huge threat to the life of the patient and seriously affect the quality of life. a heavy bur...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/00A61K35/64A61K35/65A61P35/00
Inventor 刘智谋严轶东刘露
Owner FUKANGREN BIO PHARMA
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