Reference material for assaying d-dimer

A standard substance and dimer technology, applied in the field of clinical examination, can solve the problems of stable supply, insufficient, low concentration, etc., and achieve the effect of improving diagnostic sensitivity and specificity
CN1825119AActive Publication Date: 2006-08-30SYSMEX CORP
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
SYSMEX CORP
Publication Date
2006-08-30

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Abstract

The present invention relates to a reference material for assaying D-dimer, comprising a fibrin degradation product, wherein no less than 70 % of a total peak area has the molecular weight of no less than 500,000 in a molecular weight distribution of the fibrin degradation product, measured by gel filtration chromatography.
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Description

technical field

[0001] The present invention relates to the field of clinical inspection, in particular to a standard substance for D-dimer measurement which can be used in D-dimer measurement. Background technique

[0002] Methods for measuring D-dimer are known in clinical examinations, especially in the field of blood coagulation-fibrinolysis examinations. D-dimer is one of the molecular markers of blood coagulation. Through its determination, it is useful for the diagnosis of blood coagulation, hyperfibrinolytic system, various embolisms or DIC (Diffuse Intravascular Coagulation Syndrome), and the diagnosis of the above diseases. Indexes for grasping pathological conditions and judging therapeutic effects are important.

[0003] The so-called D-dimer (D-dimer) is a polymer formed by the coagulation of fibrinogen in the blood by the action of thrombin, etc. - the fibrin obtained by decomposing stabilized fibrin by enzymes such as plasmin Degradants are a general term fo...

Claims

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