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Tumor model and method

A tumor and model technology, applied in the field of life sciences, can solve problems such as no breakthroughs in scientific research

Inactive Publication Date: 2006-11-08
叶新新
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0002] Modern medical science has carried out tumor science research at various scientific research levels for more than a century, aiming at lethal solid malignant tumors with the highest clinical natural incidence rate in the human population, such as lung cancer, gastric cancer, breast cancer, colorectal cancer, liver cancer... ; So far, no scientific research breakthroughs have been made to solve substantive problems in terms of effective prevention of cancer, effective radical cure or long-term effective remission therapy for middle-advanced lethal solid malignant tumors that have metastasized

Method used

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Embodiment Construction

[0011] In order to achieve the above object, implement the scheme that the present invention adopts:

[0012] 1. Preparation of biological experiment materials

[0013] 1.1.1 The human liver cancer MHCC97-L cell line and the human liver cancer MHCC97-H cell line established by the Liver Cancer Institute of Fudan University; the heterogeneous human liver cancer MHCC97 cell line was established from the tumor tissue of a hepatocellular carcinoma patient during clinical operation , and then separated two tumor cell clones with different tumor biological differentiation expression traits, the main tumor biological expression traits: human liver cancer MHCC97-L cell line tumor biological differentiation expression traits, a well-differentiated tumor cell clone, human liver cancer MHCC97-H The cell line has tumor biological differentiation expression traits and is a poorly differentiated tumor cell clone; the average diameter of human liver cancer MHCC97-L cells is 50±5 μm, and ther...

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Abstract

The present invention, tumor model and method, relates to life science and medicine technology. It provides one tumor model and method capable of revealing the comprehensive molecular tumor biological regulating and controlling mechanism of, the comprehensive molecular tumor biological responding mechanism of, the comprehensive molecular tumor biological preventing and treating mechanism of and medicine for human malignant solid tumor, and one comprehensive scientific human tumor model experiment platform. It also provides human molecular tumor protein expressing spectrum target capable of detecting and revealing the human small cancer-in-situ cell tissue; human molecular tumor protein expressing spectrum target capable of detecting and revealing tumor cell tissue growth and proliferation; and tumor related human gene expressing spectrum target.

Description

technical field [0001] The present invention relates to a method and drug capable of revealing the evolution and transformation of human solid malignant tumors and the microenvironment of body tissues or organs, the comprehensive molecular tumor biological regulation mechanism, the comprehensive molecular tumor biological response mechanism, the comprehensive molecular tumor biological prevention and treatment mechanism, and the drug. Models and methods, a comprehensive human tumor model scientific research experimental platform. It can reveal the detection and monitoring of human small in situ cancer cell tissues, human-related molecular tumor proteome expression profile targets; reveal the human-related molecular tumor proteome expression profile targets, tumor-related human genes that antagonize-inhibit the growth and proliferation of human tumor cell tissues Expression profiling targets. It involves the fields of life sciences and medicine. Background technique [0002...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K49/00C12N5/09
Inventor 叶新新
Owner 叶新新