Injection containing caderfloxacin lactate
A technology of injection, defloxacin, which is applied in the field of antibacterial drug injection preparations, and can solve problems such as instability and instability of aqueous solutions
Inactive Publication Date: 2006-12-13
HARBIN PHARMA GRP CO LTD GENERAL PHARMA FACTORY
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Problems solved by technology
[0011] Studies have shown that the aqueous solution of kadesfloxacin is usually unstable, especially in the environment of light and heat
Method used
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Embodiment 1
[0228] Cadefloxacin Lactate Sodium Chloride Injection [250ml] Prescription
[0229] Cadefloxacin Lactate 0.976g
[0231] Lactic acid 0.7ml (1→10)
[0232] Water for injection to 1000ml
Embodiment 2
[0234] Cadefloxacin Lactate Sodium Chloride Injection [250ml] Prescription
[0235] Cadefloxacin Lactate 1.952g
[0236] Sodium chloride 9.0g
[0237] Lactic acid 0.7ml (1→10)
[0238] Water for injection to 1000ml
Embodiment 3
[0240] Cadefloxacin Lactate Sodium Chloride Injection [250ml] Prescription
[0241] Cadefloxacin Lactate 0.976g
[0242] Sodium chloride 9.0g
[0243] Lactic acid 0.7ml (1→10)
[0244] EDTA0.1g
[0245] Water for injection to 1000ml
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The invention relates to an injection containing Caderofloxacin lactate, which comprises medicinal active constituents and pharmaceutically acceptable carrier suitable for preparing injections selected from solvent for injection, isotonic conditioning agent, pH regulator, auxiliary solvent, anti-oxidant agent, metal chelating agent, bacteria inhibitor or germicidal agent, and pain-relieving agent.
Description
Technical field: [0001] The invention relates to an antibacterial drug injection preparation, in particular to cadefloxacin lactate injection, which contains active pharmaceutical ingredients and a pharmaceutically acceptable carrier suitable for preparing injections. Background technique: [0002] Bacterial infectious diseases are common and frequently-occurring diseases, which have seriously threatened the health and life safety of the people. In terms of treatment, anti-infection therapy is the first choice at present, among which penicillins, cephalosporins and synthetic antibacterial drugs account for the vast majority. Historically, the production, sales, and clinical application of such excellent drugs have ranked first in the world. Since the 1980s, fluoroquinolone synthetic antibacterial infection drugs have been developed rapidly, and their clinical applications have become more and more extensive. Among them, ciprofloxacin, ofloxacin, sparfloxacin, and levofloxac...
Claims
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IPC IPC(8): A61K9/08A61K9/19A61K31/496A61K47/34A61P31/04A61K47/12
Inventor 朱彦民景士云赵民喜周丽梅李国峰石晓晶周淑清王伟户巧芬庄须国宋迎
Owner HARBIN PHARMA GRP CO LTD GENERAL PHARMA FACTORY