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Water needle injection containing caderofloxacin lactate

A technology of defloxacin and lactic acid card, which is applied in the field of antibacterial drug injection preparations, and can solve problems such as instability and instability of aqueous solutions

Inactive Publication Date: 2008-08-06
HARBIN PHARMA GRP CO LTD GENERAL PHARMA FACTORY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] Studies have shown that the aqueous solution of kadesfloxacin is usually unstable, especially in the environment of light and heat

Method used

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  • Water needle injection containing caderofloxacin lactate

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0254] Cadefloxacin Lactate Sodium Chloride Injection [250ml] Prescription

[0255] Cadefloxacin Lactate 0.976g

[0256] Sodium chloride 9.0g

[0257] Lactic acid 0.7ml (1→10)

[0258] Water for injection up to 1000ml

Embodiment 2

[0260] Cadefloxacin Lactate Sodium Chloride Injection [250ml] Prescription

[0261] Cadefloxacin Lactate 1.952g

[0262] Sodium chloride 9.0g

[0263] Lactic acid 0.7ml (1→10)

[0264] Water for injection up to 1000ml

Embodiment 3

[0266] Cadefloxacin Lactate Sodium Chloride Injection [250ml] Prescription

[0267] Cadefloxacin Lactate 0.976g

[0268] Sodium chloride 9.0g

[0269] Lactic acid 0.7ml (1→10)

[0270] EDTA0.1g

[0271] Water for injection up to 1000ml

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PUM

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Abstract

The invention relates to a hydro-acupuncture injection containing caderofloxacin lactate. The injection of the invention consists of active constituents of medicine and an acceptable carrier for drugs suitable for preparing injections, the carrier wherein can play a role of assistant dissolving, stabilizing, antisepticising, capacity increasing, buffering, etc. The acceptable carrier for drugs suitable for preparing injections is chosen from injection dissolvant, isotonic regulator, pH regulator, cosolvent, antioxidant, metal complexant, bacteriostatic agent or bactericide and anodyne.

Description

Technical field: [0001] The invention relates to an antibacterial drug injection preparation, in particular to cadefloxacin lactate injection, which contains active pharmaceutical ingredients and a pharmaceutically acceptable carrier suitable for preparing injections. Background technique: [0002] Bacterial infectious diseases are common and frequently-occurring diseases, which have seriously threatened the health and life safety of the people. In terms of treatment, anti-infection therapy is the first choice at present, among which penicillins, cephalosporins and synthetic antibacterial drugs account for the vast majority. Historically, the production, sales, and clinical application of such excellent drugs have ranked first in the world. Since the 1980s, fluoroquinolone synthetic antibacterial infection drugs have been developed rapidly, and their clinical applications have become more and more extensive. Among them, ciprofloxacin, ofloxacin, sparfloxacin, and levofloxac...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/496A61K47/12A61K9/08A61P31/04
Inventor 朱彦民景士云赵民喜周丽梅李国峰石晓晶周淑清王伟户巧芬庄须国宋迎
Owner HARBIN PHARMA GRP CO LTD GENERAL PHARMA FACTORY