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Pharmaceutical composition for treating gynecological inflammation and method for preparing same

A technology of gynecological inflammation and composition, applied in the field of traditional Chinese medicine, can solve problems such as obvious side effects of antibiotics, and achieve the effect of less side effects and good curative effect

Inactive Publication Date: 2006-12-27
上海慈瑞医药科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the clinical treatment of gynecological inflammation mainly uses large doses of antibiotics, and sometimes a combination of multiple antibiotics is required, making the side effects of antibiotics such as drug resistance and complications increasingly obvious

Method used

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  • Pharmaceutical composition for treating gynecological inflammation and method for preparing same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Example 1: Preparation of drop pills

[0023] Take 2 parts of Houttuynia cordata and 2 parts of eucalyptus, combine and pulverize, put into supercritical fluid extraction tank, CO 2 It is a supercritical extraction fluid, the flow rate is 2.5 liters / min, the pressure is 25MPa, the temperature is 35°C, and the time is 80 minutes to obtain Houttuynia cordata and eucalyptus volatile oil extract A;

[0024] Take 1 part of honeysuckle, extract 2 times with 70% ethanol, add 8 times of ethanol for the first time, reflux for 2 hours, pour out the extract, add 6 times of ethanol for the second time, reflux for 1 hour, combine the extracts, filter , the filtrate is decompressed, the pressure is -0.8Mpa, ethanol is recovered and concentrated, and spray-dried to obtain honeysuckle extract D;

[0025] Mix extract A and extract D to obtain extract E, mix extract E and drop pill matrix polyethylene glycol 6000 in a weight ratio of 1:2, heat to 85-90 ℃ to melt, and cool with dimethyl ...

Embodiment 2

[0026] Example 2: Preparation of Tablets

[0027] Take 1 part of extract E in Example 1, add 3 parts of medicinal starch, 0.5 part of sodium carboxymethyl cellulose, 0.3 part of β-cyclodextrin, mix evenly, granulate, and press into tablets to obtain the pharmaceutical composition of the present invention tablet.

Embodiment 3

[0028] Example 3: Preparation of capsules

[0029] Take 1 part of extract E in Example 1, add 2 parts of sodium carboxymethyl starch, mix evenly, granulate, and fill in capsules to obtain capsules of the pharmaceutical composition of the present invention.

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Abstract

The invention relates to a medicinal composition for treating gynaecologic inflammation characterized by that, the composition is prepared from the following raw materials (by weight portion): cordate houttuynia 2-6 parts, honeysuckle flower 1-4 parts, the composition can be prepared into various dosage forms including tablets, capsules, drop pills, mixture, granules, injection, suppository, effervescent tablet and subcutaneous administration preparations.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating gynecological inflammation and a preparation method thereof, belonging to the technical field of traditional Chinese medicine. Background technique [0002] Gynecological inflammation occupies a large proportion in gynecological diseases, especially cervicitis, pelvic inflammatory disease, salpingitis, vulvitis and vaginitis. At present, high-dose antibiotics are mainly used in the clinical treatment of gynecological inflammation, and sometimes a combination of multiple antibiotics is required, which makes the side effects of antibiotics such as drug resistance and complications increasingly obvious. SUMMARY OF THE INVENTION [0003] The purpose of the present invention is to provide a traditional Chinese medicine composition with good curative effect and small side effects for treating gynecological inflammation and a preparation method thereof. [0004] In order to achieve the abov...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/78A61K9/02A61K9/08A61K9/16A61K9/20A61K9/46A61K9/48A61P15/00A61P15/02
Inventor 金幸朱高峰汤磊朱益锋
Owner 上海慈瑞医药科技股份有限公司
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