Biodegradable medical extracorporeal fixing material possessing shape memory function

A biodegradable and external fixation technology, applied in the direction of prosthesis, medical science, etc., can solve the problems of burns to the skin of the parts that need to be fixed, cannot be re-molded, and is difficult for the human body to accept, and achieves less usage, easy operation and convenience The effect of the doctor's operation

Inactive Publication Date: 2007-01-03
CHANGCHUN INST OF APPLIED CHEMISTRY - CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disadvantages of common plaster fixing materials are that they cannot penetrate X-rays, are large in size, low in strength, not easy to breathe, easy to be wet, easy to break, unhygienic, not conducive to environmental protection, cumbersome to operate, and cannot be remolded. If the patient is using plaster to fix the affected area, the plaster must be removed when radiographic examination is required. If the plasticity is not good, it cannot be repaired, and it ca

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Embodiment 1 Raw material ratio (percentage by weight): polylactic acid (number average molecular weight 55,000, left-handed content is 88%) 60%, 800 order calcium carbonate 37%, gamma-aminopropyltriethoxysilane (KH-550 silane coupling agent) 1%, colorant transparent yellow 3G is 0.5%, white oil 1.5%. The material is pre-mixed according to the proportion; the mixing and granulation is completed in the twin-screw extruder. Then the prepared particles are dried in a fluidized bed to obtain special materials. Further, extruding and calendering are completed on the extruder; then the flat plate is heat-treated, punched on a punching machine, cut into different specifications, and packaged into products. Similarly, after the net extruder is extruded into a net, it is made into a net by conventional plastic processing methods such as calendering, compression molding, heat preservation, and cooling, and then cut, coiled, and packaged into a product. Similarly, it is extruded...

Embodiment 2

[0049] The number-average molecular weight of polylactic acid is 55,000, and the left-handed content is 95%. The raw material composition and preparation operation are the same as in Example 1, and the softening temperature of the product is 65°C.

Embodiment 3

[0051] The number-average molecular weight of polylactic acid is 55,000, the left-handed content is 80%, the raw material composition and preparation operation are the same as in Example 1, and the softening temperature of the product is 54°C.

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Abstract

The present invention relates to one kind of biodegradable medical extracorporeal fixing material with shape memory function. The material is polylactic acid and may have added copolymer of epsilon-caprolactone and lactide-epsilon-caprolactone, inorganic mineral, silane as cross-linking agent, coloring agent and other components. It may produced into plate through mixing, pelletizing, extruding, rolling and other steps; or into netted structure through mixing, pelletizing, extruding, weaving and other steps. When it is used, the biodegradable medical extracorporeal fixing material is first softened in warm water at 55-70 deg.c, then fixed in the required position and finally hardened after the temperature is lowered to room temperature. The present invention has excellent permeability, good water tolerance, high strength, shape memory function, capacity of being reused, no irritation to skin, degradability and other advantages.

Description

technical field [0001] The invention relates to a biodegradable medical external fixation material with shape memory. Background technique [0002] At present, gypsum and organic polymer materials are used as fixation materials in medical surgery. Among organic polymer materials, there are thermosetting foam materials and thermoplastic materials. The disadvantages of common plaster fixing materials are that they cannot penetrate X-rays, are large in size, low in strength, not easy to breathe, easy to be wet, easy to break, unhygienic, not conducive to environmental protection, cumbersome to operate, and cannot be remolded. If the patient is using plaster to fix the affected area, the plaster must be removed when radiographic examination is required. If the plasticity is not good, it cannot be repaired, and it can only be removed and redone. [0003] Although thermosetting foam materials are stronger than gypsum in terms of density, air permeability, and radiation-transmitt...

Claims

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Application Information

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IPC IPC(8): A61L27/44
Inventor 边新超庄秀丽陈学思景遐斌
Owner CHANGCHUN INST OF APPLIED CHEMISTRY - CHINESE ACAD OF SCI
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