Corydalis decumbens extract, and its preparing method and use

Abstract

The present invention discloses a Chinese medicinal material Jilong corydalis extract, its preparation method and application. Said extract contains protopine and L-tetrahydropalmatine, their summation is not less than 50% (W / W), in which the protopine content is 24%-50% (W / W), and the L-tetrahydropalmatine content is 26%-50% (W / W). The pharmological tests show that it can be used as N-methyl-D asparaginic acid acceptor antagonist and acetylcholine esterase inhibibor. Besides, said invention also provides the application of said extract in the preparation of medicine for preventing and curing the hypomnesis due to vascular dementia and senile dementia.

Description

technical field

[0001] The present invention relates to summer free extract and its preparation method and use, more particularly relates to summer free alkaloid and its preparation method and its as N-methyl-D-aspartic acid receptor antagonist and acetylcholinesterase inhibitor It is used in the preparation of drugs for preventing and treating poor memory caused by vascular dementia or senile dementia. Background technique

[0002] Vascular dementia is a disease caused by brain neuropathy caused by cerebrovascular disease and memory impairment. Cerebrovascular dementia can be caused by stroke, traumatic brain injury, and brain space-occupying lesions. Alzheimer's disease (AD), also known as Alzheimer's disease, is a degenerative brain disease caused by brain neurodegeneration that affects a variety of higher cortical functions such as memory, thinking, behavior and emotion. The etiology is unknown.

[0003] At present, the drug treatment methods for the treatment of memor...

Images