Maternal supplement

a technology of omega 3 and maternal supplement, which is applied in the field of nutritional supplements, can solve the problems that pregnant women eating a normal western diet may not be able to supply sufficient omega 3 precursors, and achieve the effect of weight and body mass index

Inactive Publication Date: 2009-06-04
NESTEC SA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0010]Accordingly, in a first aspect the present invention provides the use of docosahexaenoic acid in the manufacture of a composition for administration to a pregnant woman in at least the third trimester of pregnancy and, after delivery, to the newborn baby for a period not exceeding three months for reducing the risk of development of overweight or obesity of the baby in infancy and / or early childhood.
[0011]In a second aspect, the present invention provides the use of docosahexaenoic acid in the manufacture of a composition for administration to a pregnant woman for reducing the risk of development of overweight or obesity of the baby in infancy and / or early childhood.
[0012]In a third aspect, the present invention provides the use of docosahexaenoic acid in the manufacture of a composition for administration to a pregnant women to promote the development of lean body mass of the baby in infancy and / or early childhood.
[0013]The invention extends to a method of reducing the risk of obesity of a baby in infancy and / or early childhood by providing to a pregnant woman in need thereof a composition containing a therapeutic amount of docosahexaenoic acid.

Problems solved by technology

In particular, there are concerns that pregnant women eating a normal Western diet may not be able to supply sufficient omega 3 precursors to meet the developing foetus's need to synthesise DHA.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

EXAMPLE 1

[0041]An example of a shelf stable liquid nutritional supplement to be used according to the present invention is as follows:-

Per 100 g readyPer servingPer 100 kcalto drink(190 ml)Energy (kcal)10065130Fat (g)0.920.601.20DHA (mg)200130260(from fish oil)Protein (g)3.542.304.60Carbohydrate (g)19.412.6025.2Dietary fibre (g)3.622.354.70MineralsSodium (mg)513366Potassium (mg)238155310Chloride (mg)12380160Calcium (mg)308200400Phosphorus (mg)162105210Magnesium (mg)58.03876Selenium (μg)7.75.010.0VitaminsBeta carotene (μg)160010502100Vitamin D (μg)3.82.505.0Vitamin E (IU)4.63.06.0Vitamin C (mg)382550Vitamin B1 (mg)1.20.751.5Vitamin B2 (mg)1.30.851.7Niacin (mg)12816Vitamin B6 (mg)1.10.71.4Folic acid (μg)310200400Vitamin B12 (μg)1.20.751.5Biotin (μg)543570Trace ElementsIron (mg)127.515Iodine (μg)150100200Copper (mg)0.200.130.26Zinc (mg)3.82.55.0

example 2

[0042]This example compares the effect of administering a nutritional supplement including DHA to pregnant women with the effect of administration of the same supplement but without the DHA to a comparable group of pregnant women on the evolution of weight and body mass of their children.

[0043]A randomised, controlled, double blind, single centre clinical trial was carried out at Klinik für Geburtsmedizin, Charite, Campus Virchow Klinikum, Berlin, Germany. The study was carried out according to the principles and rules laid down in the Declaration of Helsinki (as amended). A total of 144 healthy adult Caucasian non-smoking women in the 20th to 22nd week of pregnancy willing to breastfeed for at least 3 months were recruited and assigned to one of three treatment groups. Subjects in all three groups received a daily nutritional supplement with the only difference being the content of the supplement as follows:-[0044]Group 1: Supplement (Vitamins, Minerals)[0045]Group 2: Supplement (V...

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Abstract

The use of docosahexaenoic acid in the manufacture of a composition for administration to a pregnant woman for reducing the risk of development of overweight or obesity of the baby in infancy and / or early childhood.

Description

FIELD OF THE INVENTION[0001]This invention relates to a nutritional supplement for pregnant women to reduce the risk of obesity of the baby in later life.BACKGROUND TO THE INVENTION[0002]Scientific literature suggests that supplementation of infant formula with the long chain polyunsaturated fatty acids (LC-PUFA) docosahexaenoic acid (DHA, omega 3) and arachidonic acid (ARA, omega 6) may have many health benefits for the infant. Indeed it has been demonstrated that in pre-term infants receiving DHA and ARA either from breast milk or infant formula containing these LC-PUFA demonstrate improved cognitive abilities, visual acuity and motor skills when compared with unsupplemented pre-term infants. The picture for term infants is less clear. Some studies have been published showing similar benefits of supplementation to those demonstrated with pre-term infants but other studies have found no effect of supplementation.[0003]It has been suggested that these conflicting results with term i...

Claims

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Application Information

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IPC IPC(8): A61K31/202A61K31/715A61K33/06A61K33/42A61K33/26A61K33/30A61K33/34A61K33/18A61K33/04A61K31/375A61K31/714A61K31/525A61K31/519A61K35/74A61P31/04
CPCA61K31/202A61P3/02A61P31/04A61P3/04
InventorHASCHKE, FERDINANDKRATKY, ZDENEK
OwnerNESTEC SA