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Methods and systems for supplying aerosolization devices with liquid medicaments

a technology of aerosolization device and liquid medicament, which is applied in the field of inhalers, can solve the problems of difficult delivery of a known quantity of liquid medicament,

Inactive Publication Date: 2013-10-17
DANCE BIOPHARM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The patent text describes a dispenser for medicament that can be easily operated with one hand. The dispenser has an opening that allows for easy insertion of the tip and stabilizes the dispenser in an upright position. The tip has an alignment feature that helps keep the dispenser perpendicular to the housing while dispensing the medicament. The dispenser can be repeatedly compressed to dispense multiple quantities of the medicament and can be used to aerosolize the medicament. The technical effects of the invention include increased usability and ease of operation of the dispenser.

Problems solved by technology

However, delivering a known quantity of a liquid medicament (that typically must be stored in a sterile environment) has proven to be challenging, particularly when the metered quantity needs to be dispensed in a controlled and repeatable fashion.

Method used

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  • Methods and systems for supplying aerosolization devices with liquid medicaments
  • Methods and systems for supplying aerosolization devices with liquid medicaments
  • Methods and systems for supplying aerosolization devices with liquid medicaments

Examples

Experimental program
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Embodiment Construction

[0023]Certain aspects of the invention relate to techniques for dispensing metered quantities of a liquid medicament into an aerosolizing apparatus, also referred to as an inhaler. Although useful with a wide variety of aerosolizing devices, in some cases the liquid will be dispensed into an aerosolizing apparatus comprising a housing defining a dispensing outlet or mouthpiece, a vibratable membrane or mesh having a front face exposed at the outlet and a rear face for receiving a liquid to be dispensed, and a vibrating mechanism connected to the housing and operable to vibrate the membrane to dispense aerosol of the liquid through the membrane.

[0024]A variety of containers or dispensers may be used to store the liquid medicament, then to deliver a metered quantity of the liquid into a reservoir where it will contact the rear face of the membrane. In this way, a metered quantity of liquid is dispensable at the outlet or mouthpiece by operating the vibrating mechanism for an operating...

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Abstract

A method is described for supplying a metered amount of a liquid medicament to an aerosolizing device. The method utilizes a dispenser comprising an elongate dispenser body having a proximal end and a tip at a distal end through which a liquid medicament is dispensed. The dispenser further comprises a dispensing mechanism that operates to dispense a metered quantity of the liquid medicament from the tip each time the dispenser body is compressed. The dispenser is grasped with one hand such that the fingers wrap around the dispenser body, with the thumb closest to the proximal end and the last finger closest to the tip. The tip is inserted into an opening of an inhaler and the elongate body is forced toward the tip to cause the dispenser body to compress, thereby operating the dispensing mechanism and causing a metered quantity of the liquid medicament to eject into the inhaler.

Description

CROSS REFERENCE TO RELATED APPLICATIONS[0001]This application is a nonprovisional application claiming the benefit of U.S. Provisional Application No. 61 / 624,531, filed Apr. 16, 2012, the complete disclosure of which is herein incorporated by reference.BACKGROUND OF THE INVENTION[0002]Various types of inhalers exist for aerosolizing liquids. For example, U.S. Pat. No. 5,586,550, incorporated herein by reference, describes an inhaler that comprises a dispensing apparatus in which a membrane with tapered apertures is vibrated such that liquid in contact with a rear face of the membrane is dispensed from a front face of the membrane as an aerosol. Other examples of single dose inhaler systems and medicaments that may be aerosolized are described in U.S. Patent Publication Nos. 2011 / 0168172 and 2001 / 0168170, the disclosures of which are herein incorporated by reference.[0003]One aspect of such inhalers is the need to supply a metered amount of liquid medicament to the dispensing apparat...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61M15/00
CPCA61M15/0085A61M11/005A61M15/0065A61M2209/045A61M11/00
Inventor PATTON, RYAN S.
Owner DANCE BIOPHARM
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