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116 results about "Decrease weight" patented technology

Methods for providing neuroprotection for the animal central nervous system against the effects of ischemia, neurodegeneration, trauma, and metal poisoning

Methods and pharmaceutical compositions for preconditioning and/or providing neuroprotection to the animal central nervous system against the effects of ischemia, trauma, metal poisoning and neurodegeneration, including the associated cognitive, behavioral and physical impairments. In one embodiment, the method is accomplished by stimulating and stabilizing hypoxia-inducible factor-1α (HIF-1α). HIF-1α is known to provide a neuroprotective benefit under ischemic conditions. Patients at risk for certain diseases or disorders that are associated with risk for cerebral ischemia may benefit, e.g., those at risk for Alzheimer's disease, Parkinson's disease, Wilson's disease or stroke or those patients having head or spinal cord injury. Patients undergoing certain medical procedures that may result in ischemia may also benefit. Initially, the possibility of ischemia or neurodegeneration is recognized. Intranasal therapeutic agents are administered to the upper third of the nasal cavity to bypass the blood-brain barrier and access the central nervous system directly to avoid unwanted and potentially lethal side effects. Therapeutic agents include those substances that interact with iron and/or copper such as iron chelators, copper chelators, and antioxidants. A particular example of such therapeutic agents is the iron chelator deferoxamine (DFO). Intranasal administration of DFO is known to stimulate and/or stabilize HIF-1α and provides an efficient and safe method for pre-conditioning the brain to protect against cerebral ischemia. Moreover, DFO is shown to decrease weight loss in subjects when administered pre and/or post stroke.
Owner:HEALTHPARTNERS RESEACH FOUND

Methods for providing neuroprotection for the animal central nervous system against neurodegeneration caused by ischemia

Methods and pharmaceutical compositions for preconditioning and / or providing neuroprotection to the animal central nervous system against the effects of ischemia, trauma, metal poisoning and neurodegeneration, including the associated cognitive, behavioral and physical impairments. In one embodiment, the method is accomplished by stimulating and stabilizing hypoxia-inducible factor-1α (HIF-1α). HIF-1α is known to provide a neuroprotective benefit under ischemic conditions. Patients at risk for certain diseases or disorders that are associated with risk for cerebral ischemia may benefit, e.g., those at risk for Alzheimer's disease, Parkinson's disease, Wilson's disease or stroke or those patients having head or spinal cord injury. Patients undergoing certain medical procedures that may result in ischemia may also benefit. Initially, the possibility of ischemia or neurodegeneration is recognized. Intranasal therapeutic agents are administered to the upper third of the nasal cavity to bypass the blood-brain barrier and access the central nervous system directly to avoid unwanted and potentially lethal side effects. Therapeutic agents include those substances that interact with iron and / or copper such as iron chelators, copper chelators, and antioxidants. A particular example of such therapeutic agents is the iron chelator deferoxamine (DFO). Intranasal administration of DFO is known to stimulate and / or stabilize HIF-1α and provides an efficient and safe method for pre-conditioning the brain to protect against cerebral ischemia. Moreover, DFO is shown to decrease weight loss in subjects when administered pre and / or post stroke.
Owner:HEALTHPARTNERS RESEACH FOUND

Experimental test system and method of disturbing creep of rock under pressure action of infiltration water

ActiveCN108051307AInvestigate creep propertiesRealize creep loading and unloading testMaterial strength using tensile/compressive forcesPermeability/surface area analysisFree fallingExperimental testing
The invention discloses an experimental test system and method of disturbing creep of rock under pressure action of infiltration water. According to the system, a first support pillar is fixedly arranged on a base, first and second reinforcing beams are pivoted to the first support pillar, a movable support is arranged on the second reinforcing beam and is contacted with the first reinforcing beam, one end of the first reinforcing beam is fixedly connected with a weight holder and a vibrator, a frequency modulator is externally connected with the vibrator, the vibrator produces vibration withdifferent amplitude values and different frequencies through modulation of the frequency modulator, and axial disturbance with different amplitude values and different frequencies is further producedfor a test piece; impact disturbance of different strengths is realized through free falling bodies of weights in different masses from different heights; a creep loading test can be realized by increasing or decreasing weights on the weight holder; different confining pressure and different seepage water pressure can be loaded to the test piece; experimental test of creep of the rock under the conditions of different axial pressure, different confining pressure, different seepage water pressure and different disturbing characteristics is realized, and the creep characteristic of the rock under the complicated condition can be better researched.
Owner:LIAONING TECHNICAL UNIVERSITY

Energy-storage scheduling method and device for intelligent power grid

ActiveCN106253294AJump out of the suboptimal solutionGood ability to jump out of suboptimal solutionsForecastingAc network load balancingDecrease weightSeries expansion
The invention relates to an energy-storage scheduling method and device for an intelligent power grid, and the method comprises the steps: obtaining a power generator uncertainty model, a load uncertainty model and an electric car charging uncertainty model in the intelligent power grid, wherein the intelligent power grid comprises a wind power generator, an energy storage apparatus, and an electric car charging station; carrying out the stochastic load flow calculation of the intelligent power grid through employing a two-point estimation method based on a fourth-order Gram-Charlier series expansion equation, carrying out the random sampling of a stochastic load flow calculation result, and obtaining an expected load flow distribution; determining a constraint condition according to the expected load flow distribution, solving a pre-built target function through employing a particle swarm optimization algorithm based on a segmented inertia decreasing weight, and obtaining an optimal energy storage scheme meeting the constraint condition; and carrying out the scheduling of the energy storage device according to the optimal energy storage scheme. The method can effectively inhibit the uncertainty of the intelligent power grid, and enables the intelligent power grid to operate safely and stably.
Owner:FOSHAN POWER SUPPLY BUREAU GUANGDONG POWER GRID
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