The invention discloses a screw loosening agent and a preparing method thereof. According to the technical scheme, the screw loosening agent is mainly prepared by weight by the raw materials which are 70-90 parts of solvent, 5-20 parts of antirust agents, 1-10 parts of corrosion-resistant agents and 1-10 parts of penetrants. The invention further discloses the preparing method of the screw loosening agent. The screw loosening agent has the functions of rust loosening, rust removing, penetrating, lubricating, corrosion resistance and the like, using is convenient, price is reasonable, the problem that traditional disassembling is high in difficulty and bad in effect is solved, manpower and material resources are saved, cost is saved, and great convenience is brought to production and life.