Methods of treating mitochondrial dysfunction

a mitochondrial dysfunction and treatment method technology, applied in the direction of biochemistry apparatus and processes, organic active ingredients, dna/rna fragmentation, etc., can solve the symptoms of tissue or organ dysfunction, drug side effects, and the effect of drugs only for a limited time period
US20170182076A1Inactive Publication Date: 2017-06-29ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
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Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
Publication Date
2017-06-29
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention provides methods of treating various disorders associated with mitochondrial dysfunction, including but not limited to metabolic disorders, neurodegenerative diseases, chronic inflammatory diseases, and diseases of aging.
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Description

RELATED APPLICATIONS

[0001] This application is a continuation of U.S. Ser. No. 13 / 984,157, filed Nov. 20, 2013. U.S. Ser. No. 13 / 984,157 is a national stage application, filed under 35 U.S.C. §371, of International Application No. PCT / IB2012 / 001146, filed Feb. 15, 2012, which claims the benefit of provisional applications U.S. Ser. No. 61 / 443,052 filed Feb. 15, 2011 and U.S. Ser. No. 61 / 446,303, filed Feb. 24, 2011. The contents each of which are herein incorporated by reference in their entireties.INCORPORATION OF SEQUENCE LISTING

[0002] The contents of the text file named “EPFL-003C01US_ST25.txt”, which was created on Oct. 12, 2016 and is 31 KB in size, are hereby incorporated by reference in their entiretyFIELD OF THE INVENTION

[0003] The present invention relates generally to methods of increasing intracellular NAD+ for the treatment of various mitochondrial disorders, including but not limited to metabolic disorders, neurodegenerative diseases, and chronic inflammatory diseases, and...

Claims

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