37 results about "Biomagnetism" patented technology

A tip for a biomagnetic particle transfer device generally includes a solid body made from a highly magnetically permeable material and having a shape adapted to concentrate a magnetic field generated by the transfer device on the body. The tip body preferably includes a truncated cone-shaped portion and a solid probe portion. The cone-shaped portion defines an attachment end engageable with an end of the transfer device and an apex opposite the attachment end. The probe portion extends from the apex of the cone-shaped portion, and the magnetic field is concentrated on the probe portion.

The invention discloses multifunctional intelligent acupuncture and moxibustion diagnosis and treatment instrument and an application method thereof. The diagnosis and treatment instrument comprises an acupuncture point detection module, an acupuncture point positioning module and an acupuncture and moxibustion therapy module which can be used separately or as a whole, wherein the acupuncture point detection module is used for collecting information of body surface impedance, acoustic electricity, infrared temperature, luminescence intensity, biomagnetism and electromyogram; the acupuncture point positioning module is used for lively and directly displaying the acupuncture point positions on a human 3D (three-dimensional) model, and conducting objective and accurate positioning by combining position relation of human skeleton, muscle, vessel, nerve, lymph or viscera and acupuncture points, without influence by body figure difference of users; and the acupuncture and moxibustion therapy module is used for realizing multiple treatment of oscillation massaging, infrared thermal therapy, electromagnetic treatment, pulse current treatment and the like. The multifunctional intelligent acupuncture and moxibustion diagnosis and treatment instrument and the application method thereof have the advantages of precisely detecting all physical characteristics of the acupuncture points, providing complete and reliable diagnosis reference and basis for patients and medical staff, providing accurate and reliable positioning results, and adopting multiple acupuncture and moxibustion therapymeans so as to provide convenience to users.

A tip for a biomagnetic particle transfer device generally includes a solid body made from a highly magnetically permeable material and having a shape adapted to concentrate a magnetic field generated by the transfer device on the body. The tip body preferably includes a truncated cone-shaped portion and a solid probe portion. The cone-shaped portion defines an attachment end engageable with an end of the transfer device and an apex opposite the attachment end. The probe portion extends from the apex of the cone-shaped portion, and the magnetic field is concentrated on the probe portion.

The invention relates to a biological nanometer magnetic target anti-cancer drug, which is formed by coupled biological nanometer magnetic smalls and anti-cancer chemical drug. Wherein, the biological nanometer magnetic small is nanometer magnetic particle formed in magnetic bacterial cell, at 35-120nm diameter, while its main component is Fe3O4 or Fe3S4; single magnetic particle is packed by film; and the coupled anti-cancer chemical drug comprises chemotherapy drug, nucleic acid drug, radioactive nuclide or antibody drug. The invention also provides relative production that using physical adsorption couple or based on the active function group contained by smalls and anti-cancer drug, to select right coupler via chemical reaction to couple them. And the smalls has better bioavailability, less side effect, therefore, the anti-cancer drug can be accurately transmitted to ill part via external magnetic field, to reduce the contact between drug and normal organism., to realize target positioning treatment.

The present invention recognises and eliminates from a biomagnetic measurement signal interferences whose source is disposed in the direct vicinity of an object being measured. The invention utilises the SSS method that can be used to separate from one another the signals associated with the internal and external sources of a set of measurement sensors by calculating two series developments. The sources to be examined in the invention and disposed in the so-called intermediate space produce a component to both of the developments, and can, therefore, be detected by means of an analysis to be performed in a time domain. This division into components can be made using the Principal Component Analysis (PCA), the Independent Component Analysis (ICA) or the Singular Value Decomposition. Finally, the clarified interferences in the intermediate space can be eliminated from the measured signal using, for example, the linear algebraic orthogonal projection.

The object of the invention is to provide a biomagnetism measuring device using a high-performance cylindrical shielding apparatus provided with a flange-type plate having an opening formed on a circumferential face, an auxiliary cylinder in which one or plural cylindrical members are connected so that the central axis of the opening of the flange-type plate and each central axis of the cylindrical members are coincident, cylindrical shields having first, second and third angular ranges with the y-axis, a revolving door having a cutout in a portion parallel to the y-axis and acquired by integrating the cylindrical shields, shield bases for supporting the cylindrical shield to which the flange-type plate is connected in a circular-arc part at both ends, revolving parts for revolving the revolving door in a circumferential direction of the y-axis along a circumferential part of the cylindrical shield and opening or closing an opening in the circumferential direction, a cryostat arranged inside the opening of the auxiliary cylinder and the opening and a SQUID fluxmeter arranged on a measurement face parallel to an XY plane inside the cryostat held at low temperature and characterized in that the circumferential part of the cylindrical shield is inserted between the circumferential parts of the cylindrical shields when the revolving door is closed, cylindrical internal space is formed and an environmental magnetic field that invades the internal space is screened.

A biomagnetic measurement apparatus that readily enables the positional adjustment of a test object in biomagnetic measurement and a biomagnetic measurement method are provided. In biomagnetic measurement, in the case where the test object is a heart, for example, a permanent magnet is disposed on the body surface of the xiphoid process of a subject and the pectoral region is disposed under the bottom face of the cryogenic container. A processing unit stores the calibration curve of the permanent magnet and performs a process for estimating the positional relationship between the subject and the bottom face of the cryogenic container in accordance with the measurement result of the magnetic field strength of the permanent magnet. Also, the processing unit performs a process for estimating the distance between the body surface of the test object and the bottom face of the cryogenic container.

A biomagnetic measurement apparatus having functions to detect the release of a magnetic field lock in a SQUID fluxmeter operation circuit due to the influence of a much greater noise level than that of a biomagnetic signal, to notify an operator of the release of the magnetic field lock, and to automatically or manually revert to a state for allowing magnetic measurement. The release of the magnetic field lock occurs when an integrator of the fluxmeter operation circuit is saturated. Thus, a high pass filter is provided at a subsequent stage of the integrator, and a function is provided to judge that the integrator is in a saturated state when the noise level of the output after passing through the high pass filter is lower than a pre-set threshold. The biomagnetic measurement apparatus can detect a saturated state of the integrator, which is a cause for the release of the magnetic field lock of the SQUID fluxmeter operation circuit, and thereby when the loading of measured data is conducted in an appropriate operation range of a magnetic sensor, or even when a part of the loaded measured data is data outside an operation range of the magnetic sensor, it is possible to deal with the data so as to properly analyze it.

Disclosed herein is a biomagnetic measurement apparatus capable of visualizing cardiac electrical current distributions with information on the cardiac morphology of a subject. A magnetic field component in the z direction, vertical to the chest surface of a subject, is measured from two directions, front and back of the chest, and then to calculate the current distributions in the two directions and the distributions of the amplitudes of those current distributions. A three-dimensional standard heart model is created from average data on the cardiac morphology obtained from plural healthy subjects. An optimal position of the model is determined using the coordinates of the sinus node and the coordinates of the left ventricle. Then, a weight coefficient is obtained by front and back current distributions and front and back the distributions of the amplitudes of those current distributions on a set boundary of the model.

The object of the invention is to provide a biomagnetism measuring device using a high-performance cylindrical shielding apparatus provided with a flange-type plate having an opening formed on a circumferential face, an auxiliary cylinder in which one or plural cylindrical members are connected so that the central axis of the opening of the flange-type plate and each central axis of the cylindrical members are coincident, cylindrical shields having first, second and third angular ranges with the y-axis, a revolving door having a cutout in a portion parallel to the y-axis and acquired by integrating the cylindrical shields, shield bases for supporting the cylindrical shield to which the flange-type plate is connected in a circular-arc part at both ends, revolving parts for revolving the revolving door in a circumferential direction of the y-axis along a circumferential part of the cylindrical shield and opening or closing an opening in the circumferential direction, a cryostat arranged inside the opening of the auxiliary cylinder and the opening and a SQUID fluxmeter arranged on a measurement face parallel to an XY plane inside the cryostat held at low temperature and characterized in that the circumferential part of the cylindrical shield is inserted between the circumferential parts of the cylindrical shields when the revolving door is closed, cylindrical internal space is formed and an environmental magnetic field that invades the internal space is screened.

The invention belongs to the field of biomagnetism and life health-care articles. The invention provides a jade permanent magnetic physical therapy instrument and a health-care method thereof, aiming to achieve effective health care and physiotherapy effects by a systemic energy field generated by ecological minerals and permanent magnets. The jade permanent magnetic physical therapy instrument includes a magnet bathing device and a connected jade unit that cooperatively take effect on the different parts of a human body, the magnet bathing device includes a bathing basin, a plurality of mineral pebbles having the particle size of 4-80mm are laid on the inner bottom plate of the bathing basin, a plurality of boss-shaped permanent magnetic components are symmetrically arranged under the outer bottom plate of the bathing basin, the upward polarities of the permanent magnetic components are the same, the connected jade unit is formed by the connection of a plurality of mineral plates having the area of 4-100cm<2>, and permanent magnetic small rings are arranged on the surfaces of the mineral plates. Through the adoption of the energy running water of the dissolved mineral elements and the acupoint magnetic therapy of the connected jade unit, the instrument and the health-care method thereof can uniquely cooperate with the homeopathy of quantum medicines, excites the restoration capability of a human-body self-healing system, and achieves the smooth spontaneous healing effect.

The invention provides a nano magnetic bead for nucleic acid purification. A preparation method of the nano magnetic bead includes the processes of preparation and surface modification of nano microspheres. The biologically-magnetic microspheres of certain sizes are obtained through an aqueous phase reaction, groups capable of adsorbing nucleic acid are introduced to the surfaces of the biologically-magnetic microspheres, through the character that silicon dioxide is electrified to adsorb nucleic acid, multiple complex samples can be efficiently purified, and therefore automation of nucleic acid purification is achieved and the workload of working staff is greatly reduced. The nano magnetic bead has the advantages that dispersibility is good, cost is low, particle uniformity is good, and the size of the magnetic bead is high in controllability, the nano magnetic bead can be effectively used for diagnostic reagent earlier purification and clinical nucleic acid detection, and has wide application prospects and social and economic benefits in the field of sequencing and the fields of biologically-magnetic microsphere targeted therapy and biological medicine development.

The invention relates to a biomagnetism separation method based on a movable magnetic net, and belongs to the technical field of biology. The biomagnetism separation method is used for separating or purifying biology objects labelled magnetically or labelled with magnetic beads. Through new design of the movable magnetic net, the gradient of magnetic field intensity closed to an acquisition targetis notably increased, and the catching capacity is improved. The required core components comprise the magnetic net (3), magnetic rods (1), magnetic sleeves (2), and a suspension biology object solution storing container (4). The magnetic net is a super paramagnetism film, and is magnetic in a magnetic field and is antimagnetic when being divorced from the magnetic field. The existence of the magnetic field is controlled through the situation whether the magnetic rods are in the magnetic sleeves or not,the magnetic net rotates to enable each object labelled by magnetic beads in the storing container to have high magnetic field intensity gradient, and high separation effect is realized. The magnetic net rotates under the condition of being nonmagnetic to release the objects. The separationmethod provided by the invention is suitable for separation of different amount of biology objects (exosomes, nucleic acids, proteins and the like ) by a magnetic bead method.

A magnetic shielding apparatus having a high shielding effect. With the magnetic shielding apparatus having an opening (for example, a cylindrical magnetic shielding apparatus provided with a door), the door covering the opening is electrically and / or magnetically connected to a main body by means of electrically and / or magnetically connecting members. The magnetic shielding apparatus is higher in magnetic shielding factor than the conventional magnetic shielding apparatus, and a magnetic field measuring apparatus using the magnetic shielding apparatus, capable of measuring biomagnetism generated from an inspection target (a living body), with higher sensibility than before.

The objective of the present invention is to provide a biomagnetism measuring device capable of accurately detecting biomagnetism regardless of the object to be measured. This biomagnetism measuring device (1) is provided with: a plurality of magnetic sensors (11) which detect biomagnetism of a living body (100); a retaining portion (12) including retaining holes (12a) which retain the plurality of magnetic sensors (11) with freedom to move individually; and a movement mechanism which moves the magnetic sensors (11) individually in a contacting / separating direction causing the magnetic sensors (11) to come into contact with or separate from the living body (100). As movement mechanisms there may be mentioned, for example, a pneumatic / hydraulic mechanism (20), a resilient body mechanism (30), a screw mechanism (40) and a gear mechanism (50).

A magnetic shielding apparatus having a high shielding effect. With the magnetic shielding apparatus having an opening (for example, a cylindrical magnetic shielding apparatus provided with a door), the door covering the opening is electrically and / or magnetically connected to a main body by means of electrically and / or magnetically connecting members. The magnetic shielding apparatus is higher in magnetic shielding factor than the conventional magnetic shielding apparatus, and a magnetic field measuring apparatus using the magnetic shielding apparatus, capable of measuring biomagnetism generated from an inspection target (a living body), with higher sensibility than before.

A biomagnetic measurement method, a biomagnetic measuring device, and a biomagnetic measuring system. The method and the biomagnetic measuring device includes obtaining first measurement data output from a magnetic field detector upon giving a stimulus to a subject in a first state where a site of interest of the subject is made close to the magnetic field detector, and obtaining second measurement data output from the magnetic field detector upon giving a stimulus to the subject in a second state where a site to which the stimulus is given and a position of the site to which the stimulus is given are equivalent to a site to which the stimulus is given and a position of the site to which the stimulus is given in the first state, respectively, and the site of interest of the subject is separated from the magnetic field detector with reference to the first state.

The invention discloses multifunctional intelligent acupuncture and moxibustion diagnosis and treatment instrument and an application method thereof. The diagnosis and treatment instrument comprises an acupuncture point detection module, an acupuncture point positioning module and an acupuncture and moxibustion therapy module which can be used separately or as a whole, wherein the acupuncture point detection module is used for collecting information of body surface impedance, acoustic electricity, infrared temperature, luminescence intensity, biomagnetism and electromyogram; the acupuncture point positioning module is used for lively and directly displaying the acupuncture point positions on a human 3D (three-dimensional) model, and conducting objective and accurate positioning by combining position relation of human skeleton, muscle, vessel, nerve, lymph or viscera and acupuncture points, without influence by body figure difference of users; and the acupuncture and moxibustion therapy module is used for realizing multiple treatment of oscillation massaging, infrared thermal therapy, electromagnetic treatment, pulse current treatment and the like. The multifunctional intelligent acupuncture and moxibustion diagnosis and treatment instrument and the application method thereof have the advantages of precisely detecting all physical characteristics of the acupuncture points, providing complete and reliable diagnosis reference and basis for patients and medical staff, providing accurate and reliable positioning results, and adopting multiple acupuncture and moxibustion therapy means so as to provide convenience to users.

The invention discloses a preparation method and equipment for novel biomagnetic ceramsite filling for water treatment. The preparation method comprises the steps of mixing activated magnetic powder,ceramsite, borax and titanium dioxide in a certain proportion, then mixing with water through a magnetic microbubble stirring and mixing device, performing granulation, drying, calcining, water washing, drying and magnetizing to form a magnetic ceramsite filling matrix, loading a surface material comprising coal, clay, neodymium iron boron and water on the surface of the magnetic ceramsite fillingmatrix in a rotary spray load device, and performing secondary drying, calcining and cooling to form the biomagnetic ceramsite filling. Membrane hanging is more easier; the prepared biomagnetic ceramsite filling has a promotion effect on microorganism aggregation of a biological membrane, so that the specific surface area of the surface of the biological membrane is increased; a removal effect ofthe biological membrane on pollutants is improved; ammonia-nitrogen removal efficiency can be greatly improved; and the popularization and application of the method and the equipment in actual sewage(waste water) biotreatment are facilitated.

A magnetic measuring apparatus includes an inclination gantry including a mount surface and an inclined surface that is inclined with respect to the mount surface, a cryostat disposed on the inclined surface, a cryocooling system connected to the cryostat, a sensor tube connected to the cryostat and including a curved surface that does not curve in a predetermined direction and curves in a direction orthogonal to the predetermined direction such that a center of the curved surface protrudes with respect to side edges of the curved surface, and a magnetic sensor that measures biomagnetism and is housed in the sensor tube such that a sensor surface of the magnetic sensor faces the curved surface. The sensor surface is inclined with respect to the mount surface in a direction that is the same as a direction in which the inclined surface is inclined.

A Superconducting Quantum Interference Device (SQUID) magnetic sensor system and method can image organic transplant condition, such as status, acceptance, or rejection, in-vivo. This represents a major advane in transplant imaging technology with a new market for biomagnetic sensor devices. In-vivo transplant condition determination provides a greater range of imaging methodologies over existing methods in sensitivity, and enables early detection of rejection with the ability to determine the need for anti-rejection drugs.

A magnetic measuring apparatus includes an inclination gantry including a mount surface and an inclined surface that is inclined with respect to the mount surface, a cryostat disposed on the inclined surface, a cryocooling system connected to the cryostat, a sensor tube connected to the cryostat and including a curved surface that does not curve in a predetermined direction and curves in a direction orthogonal to the predetermined direction such that a center of the curved surface protrudes with respect to side edges of the curved surface, and a magnetic sensor that measures biomagnetism and is housed in the sensor tube such that a sensor surface of the magnetic sensor faces the curved surface. The sensor surface is inclined with respect to the mount surface in a direction that is the same as a direction in which the inclined surface is inclined.

The invention relates to a medical instrument, in particular to a multiple-effect prostate therapeutic instrument which comprises the following four main parts: a controller, a combined therapeutic head, a display and a printer; wherein the combined therapeutic head, the display and the printer are all connected with the controller. The controller consists of a singlechip, a switch power supply, apower output circuit, a power push circuit, computers, a signal preamplification circuit and a sampling feedback circuit; the computer, the power output circuit, the power push circuit, the computer,the signal preamplification circuit and the sampling feedback circuit are all connected with the singlechip. The multiple-effect prostate therapeutic instrument has the advantages that the therapeutic head is directly applied to the focus of a patient by using a modern optical principle, biomagnetism and an electronic control technology, ensuring the effects of immunoregulation, blood activationand stasis dissolution, detumescence, antiphlogosis and acesodyne, blood circulation promotion and circulation without pain, thereby achieving the therapeutic purposes of recovering organism functionsand eliminating inflammation.

The invention relates to a preparation method of a porous magnetic conductive biological ceramic electrode for a microbial fuel cell. The preparation method comprises the steps of the preparation of a porous ceramic plate, preparation of an anode electrode and preparation of a cathode electrode. By utilizing the advantages and the characteristics of conductivity and biocompatibility of a porous ceramic, the surface area of the electrode is increased, the electrode has biomagnetism, and is favorable for biofilm colonization and stripping, and the function of a biofilm in the electrode is improved; meanwhile, the electrode has the characteristics of good waterproof performance, good conductivity, good air permeability, low synthesis cost, and short production time, and thus has broad market prospects.

The invention discloses a HPM high precision minimally invasive ablation orthotic device and an ablation orthotic method thereof; the method and device can solve the disadvantages of a conventional treatment method, push the minimally invasive treatment of Hallux Valgus symptom to a whole new level, combine the whole new minimally invasive technology with the shaping technology to cure the HalluxValgus, leave no wound on soft tissues, cannot hurt leg nerves, do not move ligaments, cannot hurt joints, can reset foot thumb joints, and can realize stitch-free, scar-free, painless, hospitalization-free, leave-at-cure, and sequelae-free advantages; sequelae does not appear after treatment according to clinic patient application observation. The biomagnetism technology, the microscopic technology, the nanometer minimally invasive technology and the ablation technology are combined so as to greatly improve the minimally invasive shaping effect, thus starting a Hallux Valgus treatment new era.

A Superconducting Quantum Interference Device (SQUID) magnetic sensor system and method can image organic transplant condition, such as status, acceptance, or rejection, in-vivo. This represents a major advane in transplant imaging technology with a new market for biomagnetic sensor devices. In-vivo transplant condition determination provides a greater range of imaging methodologies over existing methods in sensitivity, and enables early detection of rejection with the ability to determine the need for anti-rejection drugs.

A device includes a longitudinal member having a proximal end and a distal end. The longitudinal member is configured to be located proximate a tissue region within a patient. The measurement device is configured and dimensioned to be proximal to the distal end of the longitudinal member. The measurement device includes a magnetic sensor configured to measure biomagnetism and output magnetic flux data. A signal processing device is coupled to the magnetic sensor and configured to convert the output magnetic flux data into a digital representation of the output magnetic flux data. A method of measuring electrical activity using the device is also disclosed.

The invention discloses a dynamic magnetization water washing footbath: according to the biomagnetism effect principle, the dynamic magnetization water washing footbath uses the permanent magnet and water pump for acting on the water flow rate for having magnetic water resonance device, the physical structure and chemical composition of the mineral substance in the water are changed under the condition that the intrinsic chemical composition of the water is not changed, the common water is cut by the magnetic line in the footbath additional device at certain flow rate for changing the common water into the dynamic magnetization water.

The invention relates to a readout circuit based on SQUID (Superconducting Quantum Interference Device) offset voltage reversal and a method for inhibiting low-frequency noise. The readout circuit is characterized in that the offset reversal is realized by an offset reversal circuit in order to inhibit the generation of the low-frequency noises; and particularly, the readout circuit comprises an SBC(SQUID Boottrap Circuit)-structured SQUID low temperature part and an offset reversal readout circuit part. The main process of the method comprises the steps of: (1) regulating an input offset voltage in an amplifier; (2) loading an alternating-current square-wave offset voltage; (3) regulating a flux phase and compensating direct-current flux; (4) eliminating carrier waves; and (5) outputting in an integral feedback manner. The circuit related by the invention is simpler in structure and convenient for multi-channel integration, and can be widely applied to low-frequency measurements such as biomagnetism and geophysical exploration, etc.

The invention belongs to the field of biomagnetism and life health-care articles. The invention provides a jade permanent magnetic physical therapy instrument and a health-care method thereof, aiming to achieve effective health care and physiotherapy effects by a systemic energy field generated by ecological minerals and permanent magnets. The jade permanent magnetic physical therapy instrument includes a magnet bathing device and a connected jade unit that cooperatively take effect on the different parts of a human body, the magnet bathing device includes a bathing basin, a plurality of mineral pebbles having the particle size of 4-80mm are laid on the inner bottom plate of the bathing basin, a plurality of boss-shaped permanent magnetic components are symmetrically arranged under the outer bottom plate of the bathing basin, the upward polarities of the permanent magnetic components are the same, the connected jade unit is formed by the connection of a plurality of mineral plates having the area of 4-100cm<2>, and permanent magnetic small rings are arranged on the surfaces of the mineral plates. Through the adoption of the energy running water of the dissolved mineral elements and the acupoint magnetic therapy of the connected jade unit, the instrument and the health-care method thereof can uniquely cooperate with the homeopathy of quantum medicines, excites the restoration capability of a human-body self-healing system, and achieves the smooth spontaneous healing effect.