This invention discloses a quaternized
pullulan /
cellulose composite hemostatic
sponge containing
snail mucus, its preparation method, and its application, belonging to the field of biomedical materials technology. The quaternized
pullulan /
cellulose composite hemostatic
sponge containing
snail mucus is obtained by cross-linking hydroxypropyl methylcellulose, quaternized
pullulan polysaccharide, and
snail mucus powder with a cross-linking agent; the
mass ratio of hydroxypropyl methylcellulose, quaternized pullulan
polysaccharide, and snail mucus is 1.9-2.1:1:3.8-4.2. The quaternized pullulan /
cellulose composite hemostatic
sponge containing snail mucus of this invention can solve the problems of insufficient
porosity, poor wet
tissue adhesion, single hemostatic mechanism, and low functional integration of existing hemostatic materials.