Footwear components apply heat, cooling, and / or pressure to a wearer's foot / leg /
ankle. Such footwear includes one or more of: (a) an interior upper layer formed from one or more interior upper component parts; (b) an exterior upper layer formed from one or more exterior upper component parts and engaged with the interior upper layer, wherein the interior and exterior upper
layers define an
ankle-receiving chamber of the footwear upper; (c) a fluid-filled bladder
system including a first fluid chamber located between the interior and exterior upper
layers; (d) a heating and / or cooling
system having at least a portion engaged with the first fluid chamber; (e) a fluid source component (e.g., pump, compressor, etc.) in fluid communication with the first fluid chamber and configured to supply fluid to the first fluid chamber; (f) a power source; and / or (g) a securing
system for releasably securing the footwear upper to a wearer's foot / leg /
ankle.