2results about How to "Short hemostatic time" patented technology

This invention belongs to the field of biomedical materials technology, specifically relating to an oxidized hyaluronic acid / carboxymethyl chitosan hemostatic sponge and its preparation method. The preparation method includes: oxidizing hyaluronic acid with sodium periodate to obtain oxidized hyaluronic acid; preparing aqueous solutions of oxidized hyaluronic acid and carboxymethyl chitosan; mixing the two solutions and forming a hydrogel through a Schiff base reaction between aldehyde and amino groups; cryogelatinizing the hydrogel at low temperature and then freeze-drying it under vacuum to obtain an expandable hemostatic sponge with a three-dimensional interconnected porous structure. Upon contact with blood, the sponge of this invention rapidly absorbs water and expands, increasing in volume by more than three times, forming a tight physical seal. Simultaneously, it adsorbs and activates platelets to accelerate coagulation, achieving highly efficient hemostasis. This sponge exhibits excellent biocompatibility, is completely degradable in vivo, and the preparation process is mild and requires no toxic cross-linking agents. It can be used for rapid hemostasis of deep, irregular, and non-compressible bleeding wounds.

The present application belongs to the technical field of medical hemostatic dressings and bandages, and particularly relates to a Duyuwei emergency hemostatic bandage, which comprises a bandage main body, the bandage main body is composed of a tight band and a dressing pad, the dressing pad is fixed to the front end of the tight band, the dressing pad is composed of an absorption area, a tablet area and a pad base layer, the absorption area and the tablet area are fixed on the pad base layer by traditional Chinese medicine glue, the absorption area is composed of Duyuwei gelatin sponge, the tablet area is composed of Duyuwei external-use tablets, and the pad base layer is composed of a medical degreasing cotton pad. A preparation method of the Duyuwei emergency hemostatic bandage comprises the following steps: Duyuwei medicinal material decoction piece component extraction, Duyuwei external-use tablet preparation, traditional Chinese medicine glue preparation, Duyuwei gelatin sponge preparation and Duyuwei hemostatic bandage preparation. The present application has the advantages of rapid hemostasis and remarkable efficacy: the Duyuwei extract, the gelatin sponge and the traditional Chinese medicine glue synergistically act to significantly shorten the hemostasis time. Animal experiments show that the average hemostasis time is short.