50results about How to "Short hemostatic time" patented technology

The invention relates to a medical compound micropore polysaccharide and application in hemostasis on wound surface bleeding areas of various wounds and operation tissues. The medical compound micropore polysaccharide is prepared by adopting a method with the following steps: (1) preparing starch fluid; (2) preparing carboxymethyl chitosan solution; (3) mixing the starch fluid and the carboxymethyl chitosan solution, and adding dispersant and emulsifier into the mixture; (4) emulsifying, crosslinking and co-polymerizing; and (5) refining, drying, packing and sterile treatment. The invention also discloses application of the medical compound micropore polysaccharide in preparing a hemostasis medicament used for the wound surface bleeding areas of wounds and operation tissues. The medical compound micropore polysaccharide of the invention has the following characteristics: 1, the hemostasis time is short, namely the hemostasis is generally finished in 3 to 5 minutes; 2, the medical compound micropore polysaccharide has no antigenicity, has polysaccharide components, and has no protein or immune reaction; 3, the medical compound micropore polysaccharide can be fully degraded and absorbed in vivo; 4, the medical compound micropore polysaccharide is a sterile product and is convenient to use by opening; and 5, the tissue reaction is light. Therefore, the medical compound micropore polysaccharide is a comparatively ideal surgical hemostasis product.

The invention discloses a half-path charge complementary type chiral self-assembled short-peptide nanometer biomedical material and application. The general formula of the amino acid sequence of a chiral self-assembled short peptide provided in the invention is shown as follows: Ac-Pro-X-Phe-Y-Phe-Asn-Phe-Gln-Pro-NH2, wherein X and Y are polar charged amino acids, X is an negatively charged amino acid and Y is an positively charged amino acid, the amino acids of the whole peptide chain are all D-amino acid, and the number of amino acid residues is set as 9. The half-path charge complementary type chiral self-assembled short peptide has a secondary structure with relatively strong stability and is hardly influenced by external environmental factors, the self-assembly morphology of the chiral short peptide can be regulated by adding NaCl or changing the content of NaCl, and nanometer fiber hydrogel, which has rapid bleeding-stopping effect on bleeding wound, can be formed through self assembly. The material is simple and practicable in preparation technology and relatively low in cost, and the application of the material helps to enrich the kinds of nanometer biomedical materials.