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Pharmaceutical composition for treating liver disease and its preparation and application

A composition and functional technology, applied in the direction of drug combination, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve problems such as unsatisfactory curative effect

Inactive Publication Date: 2008-05-14
北京万赛生物医药技术发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The technical problem to be solved in the present invention is to overcome the unsatisfactory defects of the existing drugs for treating hepatitis, and provide a pharmaceutical composition with the function of treating liver diseases, its preparation method and application

Method used

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  • Pharmaceutical composition for treating liver disease and its preparation and application
  • Pharmaceutical composition for treating liver disease and its preparation and application
  • Pharmaceutical composition for treating liver disease and its preparation and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Example 1 Preparation of Extract

[0024] Crushing of medicinal materials: weigh the honeysuckle, bake it at 80°C for 1 hour, and crush it into a coarse powder under heat, with a yield of about 95%. Mung beans (the medicinal materials should pass the inspection) are crushed into coarse powder with a roller compactor, and the fine powder below 100 mesh is sieved, and the yield is about 95%.

[0025] Honeysuckle coarse powder, add 10 times the amount of 75% ethanol, soak for 20min, reflux for 2h, filter, drain to obtain alcohol extract I and dregs, add 8 times the amount of 75% ethanol for dregs, reflux for 0.5h, filter, drain Dry to obtain the alcohol extract II and medicinal residues, discard the medicinal residues and combine the alcohol extractions I and II, recover ethanol under reduced pressure to form a concentrated solution with a relative density of about 1.08 (70°C), filter, and spray dry to obtain the honeysuckle extract.

[0026] Mung bean coarse powder, add ...

Embodiment 2

[0027] The preparation of embodiment 2 granules

[0028] The honeysuckle extract and mung bean extract are uniformly mixed according to the weight ratio of 1:0.1, dextrin or dextrin and sweetener are added, granulated, dried, whole grains are packed into bags to form granules.

Embodiment 3

[0029] The preparation of embodiment 3 capsules

[0030] The honeysuckle extract and mung bean extract are uniformly mixed according to the ratio of 1:4, dry granulated (through a 10-mesh sieve), packed into capsules, and packaged to obtain the product.

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Abstract

The invention discloses a pharmaceutical composition for treating liver diseases, wherein the active constituent being the mixture of ethanol extractive of honeysuckle flower and aqueous extract of mung bean. The process for preparing the composition includes the steps of disintegrating, ethanol extracting, concentrating and drying, and mixing with pharmaceutically acceptable excipient.

Description

technical field [0001] The invention relates to a pharmaceutical composition capable of treating liver diseases, a preparation method and application. Background technique [0002] Chronic liver disease (inflammation) is a common clinical disease frequently-occurring disease, and hepatitis B is an infectious liver disease caused by hepatitis B virus (HBV). More than 2 billion people in the world have been infected, and about 350 million people have become chronic HBV infections. Chronic carriers are prone to liver cirrhosis and liver cancer. More than 1 million patients die of liver disease every year in the world, 1 / 3 of which are in China. In addition, mothers of HBV carriers can transmit it to their babies vertically. More than 90% of those infected with HBV during their infancy will become chronic HBsAg carriers, which will affect the health of the next generation and cause great harm. [0003] Hepatitis cannot be cured in a short time. Because the course of hepatitis...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/48A61P1/16A61P31/14A61P31/20
Inventor 李求是
Owner 北京万赛生物医药技术发展有限公司