Nanometer Chinese traditional medicine for treating osteoporosis

A technology for osteoporosis and nano-Chinese medicine, which can be used in bone diseases, drug combinations, pharmaceutical formulations, etc., and can solve problems such as poor drug absorption and bioavailability

Inactive Publication Date: 2008-06-04
辽宁中医学院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Therefore, the development of a nano-Chinese medicine for the prevention and treatment of osteoporosis to solve the problems of poor absorption and bioavailability of drugs for the treatment of osteoporosis has always been a new topic to be solved urgently at home and abroad.

Method used

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  • Nanometer Chinese traditional medicine for treating osteoporosis
  • Nanometer Chinese traditional medicine for treating osteoporosis
  • Nanometer Chinese traditional medicine for treating osteoporosis

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Embodiment Construction

[0004] The embodiment of the present invention is as follows, 500g of oysters are roughly crushed by a crocodile crusher, screened by a vibrating screen, thrown away impurities, deep-frozen by ultra-low temperature liquid nitrogen, and ball-milled with high-frequency machine vibration or high-energy ball mill to make the particle size reach 200nm The following is to make nano oyster calcium; 500g of active velvet antler is aseptically taken fresh velvet velvet, immediately frozen in liquid nitrogen, stored at -70°C, cut into thin slices when making pharmaceuticals, and crushed after freeze-drying; 750g of ginseng was crushed into fine powder; 750g of Eucommia Reflux extraction with 70% ethanol for 2 times, combine the 2 extracts, filter, recover ethanol, concentrate into a clear paste; add 750g of tortoise shell to decoct for 2 hours, filter, add eucommia dregs, 750g of rehmannia glutinosa, and 750g of kudzu root, Add water to decoct twice, combine the decoction, filter, combin...

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Abstract

The present invention is one kind of nano Chinese medicine for preventing and treating osteoporosis, and belongs to the field of biological pharmacology. The medicine recipe consists of oyster, active pilose antler, prepared rhizome of rehmannia, kudzu vine root, eucommia bark, ginseng and tortoise plastron. The preparation process includes nano technological process to prepare oyster calcium, freeze drying to prepare active pilose antler, crushing ginseng into fine powder, alcohol extracting eucommia bark, merging water decoction of tortoise plastron, prepared rhizome of rehmannia and kudzu vine root, decompression evaporation to obtain fine powder, mixing and pelletizing to form the medicine. The medicine has the advantages of benefiting vital energy and life essence, strengthening kidney, replenishing calcium, etc. and has obvious osteoporosis preventing and treating effect.

Description

Technical field: [0001] The invention relates to a nanometer traditional Chinese medicine for preventing and treating osteoporosis in the field of biopharmaceuticals. Background technique: [0002] Osteoporosis is a common and frequently-occurring disease of the elderly. The number of people in need of prevention and treatment of osteoporosis is more than 100 million, and there is an increasing trend year by year. With the increase of the aging population, the prevalence of osteoporosis and the incidence of its complications are also increasing; fractures and their complications caused by osteoporosis have become an important disease that reduces the quality of life and dies of the elderly. It is known that the etiology of primary osteoporosis is closely related to endocrine factors and calcium balance disorders. Recent foreign research involves receptors (estrogen receptors, PTH receptors, CT receptors, etc.), genes (VDR alleles, estrogen receptor genes, etc.), and factors...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61K36/48A61K36/46A61K36/258A61K35/56A61K35/32A61P19/10A61K35/586A61K35/618
Inventor 郑洪新何慧明任路
Owner 辽宁中医学院
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