Effervescence tablet for treating wind-cold type cold and preparation process thereof

Abstract

The invention relates to a Ganmao Qingre effervescent tablet and a preparation method thereof, belonging to the field of traditional Chinese medicines. The effervescent tablet is composed of Ganmao heat-clearing extract powder, beta-cyclodextrin inclusion complex, acid agent, alkali agent, sweetener, filler and lubricant. The invention has reasonable types and dosages of auxiliary materials and the ratio of main ingredients, simple preparation process, stable quality of effervescent tablets, and good effervescent effect. At the same time, cyclodextrin is used to contain volatile oil, which reduces the loss of volatile oil and improves taste. The invention is a Ganmaoqingre effervescent tablet with high bioavailability, quick onset, convenient taking, stable quality, good taste, convenient transportation and carrying and a preparation method thereof.

Description

technical field

[0001] The invention belongs to the field of traditional Chinese medicine pharmacy, and more specifically relates to a Ganmao Qingre effervescent tablet and a preparation method thereof. Background technique

[0002] The original preparation Ganmao Qingre Granule has the functions of dispelling wind and cold, relieving exterior and clearing heat. It is used for the treatment of wind-cold cold, headache and fever, aversion to cold and body pain, runny nose, cough and dry throat, and the effect is exact. But its preparation volume is bigger, and it is inconvenient to carry, and mouthfeel is bad. However, after the medicine is changed to Ganmaoqingre effervescent tablet, compared with granules, the volume is small, and it can be taken directly after the effervescence dissolves.

[0003] Ganmao Qingre Effervescent Tablets are effervescent tablets made by reforming the dosage form of Ganmao Qingre Granules. Oral effervescent tablet is a new type of immediate-rel...

Examples

Embodiment 1

[0043] According to the share of each raw material in Ganmao Qingre Effervescent Tablets, take the following prescription raw materials (in grams) for subsequent use:

[0044] Nepeta ear 1500g Mint 450g Fangfeng 750g Bupleurum 750g Perilla leaf 450g

[0045] Pueraria root 750g Bellflower 450g Bitter almond 600g Angelica dahurica 450g Kudiding 1500g

[0046] Reed root 1200g

[0047] (1) Take Nepeta chinensis, mint, perilla leaves, add 10 times the amount of water, soak for 2 hours, steam distill for 6 hours to extract the volatile oil, collect the distilled aqueous solution in another device, and use the dregs for later use; Essence-water 1:8:80 inclusion volatile oil, stirred at 50°C for 1 hour, refrigerated overnight, filtered, dried at 40°C, and pulverized into fine powder to obtain beta-cyclodextrin inclusion complex.

[0048] (2) Add 12 times the amount of water to the dregs and other Bawei such as Fangfeng, decoct twice for 1.5 hours each time, combine the decoction, fi...

Embodiment 2

[0051] According to the share of each raw material in Ganmao Qingre Effervescent Tablets, take the following prescription raw materials (in grams) for subsequent use:

[0052] Nepeta ear 1500g Mint 450g Fangfeng 750g Bupleurum 750g Perilla leaf 450g

[0053] Pueraria root 750g Bellflower 450g Bitter almond 600g Angelica dahurica 450g Kudiding 1500g

[0054] Reed root 1200g

[0055](1) Take Nepeta chinensis, mint, perilla leaves, add 10 times the amount of water, soak for 2 hours, steam distill for 6 hours to extract the volatile oil, collect the distilled aqueous solution in another device, and use the dregs for later use; Essence-water 1:8:80 inclusion volatile oil, stirred at 50°C for 1 hour, refrigerated overnight, filtered, dried at 40°C, and pulverized into fine powder to obtain beta-cyclodextrin inclusion complex.

[0056] (2) Add 12 times the amount of water to the dregs and other Bawei such as Fangfeng, decoct twice for 1.5 hours each time, combine the decoction, fil...

Embodiment 3

[0059] According to the share of each raw material in Ganmao Qingre Effervescent Tablets, take the following prescription raw materials (in grams) for subsequent use:

[0060] Nepeta ear 1500g Mint 450g Fangfeng 750g Bupleurum 750g Perilla leaf 450g

[0061] Pueraria root 750g Bellflower 450g Bitter almond 600g Angelica dahurica 450g Kudiding 1500g

[0062] Reed root 1200g

[0063] (1) Take Nepeta chinensis, mint, perilla leaves, add 10 times the amount of water, soak for 2 hours, steam distill for 6 hours to extract the volatile oil, collect the distilled aqueous solution in another device, and use the dregs for later use; Essence-water 1:8:80 inclusion volatile oil, stirred at 50°C for 1 hour, refrigerated overnight, filtered, dried at 40°C, and pulverized into fine powder to obtain beta-cyclodextrin inclusion complex.

[0064] (2) Add 12 times the amount of water to the dregs and other Bawei such as Fangfeng, decoct twice for 1.5 hours each time, combine the decoction, fi...

technical field

[0001] The invention belongs to the field of traditional Chinese medicine pharmacy, and more specifically relates to a Ganmao Qingre effervescent tablet and a preparation method thereof. Background technique

[0002] The original preparation Ganmao Qingre Granule has the functions of dispelling wind and cold, relieving exterior and clearing heat. It is used for the treatment of wind-cold cold, headache and fever, aversion to cold and body pain, runny nose, cough and dry throat, and the effect is exact. But its preparation volume is bigger, and it is inconvenient to carry, and mouthfeel is bad. However, after the medicine is changed to Ganmaoqingre effervescent tablet, compared with granules, the volume is small, and it can be taken directly after the effervescence dissolves.

[0003] Ganmao Qingre Effervescent Tablets are effervescent tablets made by reforming the dosage form of Ganmao Qingre Granules. Oral effervescent tablet is a new type of immediate-rel...

Examples

Embodiment 1

[0043] According to the share of each raw material in Ganmao Qingre Effervescent Tablets, take the following prescription raw materials (in grams) for subsequent use:

[0044] Nepeta ear 1500g Mint 450g Fangfeng 750g Bupleurum 750g Perilla leaf 450g

[0045] Pueraria root 750g Bellflower 450g Bitter almond 600g Angelica dahurica 450g Kudiding 1500g

[0046] Reed root 1200g

[0047] (1) Take Nepeta chinensis, mint, perilla leaves, add 10 times the amount of water, soak for 2 hours, steam distill for 6 hours to extract the volatile oil, collect the distilled aqueous solution in another device, and use the dregs for later use; Essence-water 1:8:80 inclusion volatile oil, stirred at 50°C for 1 hour, refrigerated overnight, filtered, dried at 40°C, and pulverized into fine powder to obtain beta-cyclodextrin inclusion complex.

[0048] (2) Add 12 times the amount of water to the dregs and other Bawei such as Fangfeng, decoct twice for 1.5 hours each time, combine the decoction, fi...

Embodiment 2

[0051] According to the share of each raw material in Ganmao Qingre Effervescent Tablets, take the following prescription raw materials (in grams) for subsequent use:

[0052] Nepeta ear 1500g Mint 450g Fangfeng 750g Bupleurum 750g Perilla leaf 450g

[0053] Pueraria root 750g Bellflower 450g Bitter almond 600g Angelica dahurica 450g Kudiding 1500g

[0054] Reed root 1200g

[0055](1) Take Nepeta chinensis, mint, perilla leaves, add 10 times the amount of water, soak for 2 hours, steam distill for 6 hours to extract the volatile oil, collect the distilled aqueous solution in another device, and use the dregs for later use; Essence-water 1:8:80 inclusion volatile oil, stirred at 50°C for 1 hour, refrigerated overnight, filtered, dried at 40°C, and pulverized into fine powder to obtain beta-cyclodextrin inclusion complex.

[0056] (2) Add 12 times the amount of water to the dregs and other Bawei such as Fangfeng, decoct twice for 1.5 hours each time, combine the decoction, fil...

Embodiment 3

[0059] According to the share of each raw material in Ganmao Qingre Effervescent Tablets, take the following prescription raw materials (in grams) for subsequent use:

[0060] Nepeta ear 1500g Mint 450g Fangfeng 750g Bupleurum 750g Perilla leaf 450g

[0061] Pueraria root 750g Bellflower 450g Bitter almond 600g Angelica dahurica 450g Kudiding 1500g

[0062] Reed root 1200g

[0063] (1) Take Nepeta chinensis, mint, perilla leaves, add 10 times the amount of water, soak for 2 hours, steam distill for 6 hours to extract the volatile oil, collect the distilled aqueous solution in another device, and use the dregs for later use; Essence-water 1:8:80 inclusion volatile oil, stirred at 50°C for 1 hour, refrigerated overnight, filtered, dried at 40°C, and pulverized into fine powder to obtain beta-cyclodextrin inclusion complex.

[0064] (2) Add 12 times the amount of water to the dregs and other Bawei such as Fangfeng, decoct twice for 1.5 hours each time, combine the decoction, fi...

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