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Traditional Chinese medicine for treating coronary heart disease and angina pectoris and its preparation method

A coronary heart disease angina pectoris and composition technology, applied in the field of traditional Chinese medicine, can solve problems such as unstable quality, inconvenience in taking medicine, time-consuming and labor-intensive treatment, etc., and achieve the effect of improving myocardial ischemia, good curative effect, and reducing oxygen consumption

Active Publication Date: 2007-10-17
ZHONGJING WANXI PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine decoction treatment is time-consuming and labor-intensive, and the quality is unstable, making it inconvenient to take medicine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] The preparation of embodiment 1 oral liquid

[0031] 1) Weigh each raw material according to the following weight: Sanqi 99g, Codonopsis 333g, Earthworm 222g, Corydalis Corydalis (roasted with vinegar) 166g, Tinglizi (stir-fried) 222g, Scallop 222g, Cinnamon 33g, Menthol 0.5g, Borneol 2g;

[0032] 2), the cinnamon is infiltrated with 5 times the weight of water, and through steam distillation, the distillate is collected to be equivalent to 3 times the weight of the crude drug, and kept in a sealed container;

[0033] 3) Heat and reflux the coarse powder of Panax notoginseng and corydalis with 4 times the weight of 50-90% ethanol to extract 3 times, 1 hour / time. Recover ethanol from the extract until it has no alcohol smell, the specific gravity is 1.05 (measured at room temperature), add distilled water and 0.3 g of sodium benzoate accounting for 1 / 3 to 2 / 3 of the total weight of the extract, adjust the pH to 4.0-5.0, stir well, and refrigerate After 24 hours, filter...

Embodiment 2

[0039] The preparation of embodiment 2 tablet

[0040] 1) Weigh each raw material according to the following weight: Panax notoginseng 60g, Codonopsis 150g, Dilong 100g, Corydalis Corydalis (roasted with vinegar) 80g, Tinglizi (stir-fried) 80g, Scallop 110g, Cinnamon 10g, Menthol 0.2g, Borneol 1g ;

[0041] 2), add 8 times the weight of water to cinnamon, collect the distillate by steam distillation until it is clear, redistill the distillate twice until the distillate becomes clear, let it stand, separate the lower oil layer, collect the volatile oil, and use the dregs for later use;

[0042]3) Heat and reflux the coarse powder of Panax notoginseng and corydalis with 4 times the weight of 50-90% ethanol to extract 3 times, 3 hours / time. Recover ethanol from the extract until it has no alcohol smell, the specific gravity is 1.10 (measured at room temperature), add distilled water and 0.3 g of sodium benzoate accounting for 1 / 3 of the total weight of the extract, adjust the pH...

Embodiment 3

[0047] The preparation of embodiment 3 capsules

[0048] 1) Weigh each raw material according to the following weights: 130g Panax notoginseng, 450g Codonopsis pilosula, 350g Dilonga, 250g Corydalis corydalis, 330g fried Tinglizi, 300g scallion, 60g cinnamon, 0.8g menthol, 3g borneol;

[0049] 2), add 12 times the weight of water to cinnamon, collect the distillate by steam distillation until it is clear, redistill the distillate twice until the distillate becomes clear, let it stand, separate the lower oil layer, collect the volatile oil, and use the dregs for later use;

[0050] 3), the coarse powder of Panax notoginseng and corydalis is heated and refluxed with 8 times the weight of 50-90% ethanol to extract 3 times, 3 hours / time; the ethanol is recovered from the extract until it has no alcohol smell, and the specific gravity is 1.05 (measured at room temperature). Distilled water 2 / 3 times the total weight of the extract and 0.3g of sodium benzoate, adjust the pH value to...

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PUM

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Abstract

Disclosed is a Chinese medicinal composition for treating angina pectoris comprising the raw materials in weight ratio: notoginseng 60-130 portions, asiabell 150-450 portions, earthworm 100-350 portions, corydalis tuber (prepared by vinegar) 80-250 portions, peppergrass (fried) 80-330 portions, long stamen onion (fried) 110-300 portions, cassia bark 10-60 portions, menthol 0.2-0.8 portion and borneol 1-3 portions. The medicinal composition can be prepared by routine preparation process into an oral formulation, preferably an oral liquid. The pharmacy and clinical observation prove that the Chinese medicinal composition has confirmed efficacy in treating angina pectoris, the application is safe and no side or toxic effect will be occurred.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a Chinese medicinal composition prepared from Chinese herbal medicines as raw materials for treating angina pectoris of coronary heart disease and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] Chest impediment (angina pectoris of coronary heart disease) is caused by the inability of the coronary vessels to supply oxygen and nutrients and eliminate metabolites to meet the needs of heart activity. The clinical manifestations are heart pain (angina pectoris), arrhythmia, and myocardial infarction. The disease is a common and frequently-occurring disease that endangers human physical and mental health, and is one of the diseases that are currently being studied in middle-aged and elderly medicine. Chest obstruction (angina pectoris of coronary heart disease) is one of the important types of coronary heart disease. W...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8962A61K9/08A61K9/10A61K9/16A61K9/20A61K9/48A61P9/10A61K31/045A61K35/62
Inventor 孙耀志
Owner ZHONGJING WANXI PHARMA CO LTD
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