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Composition of Chinese traditional medicine for treating diabetes, and preparation method

A composition and technology for diabetes, applied in the directions of drug combination, pharmaceutical formula, drug delivery, etc., can solve the problems of lack of left-hand side, prescription, many side effects, and little preventive effect on chronic complications of diabetes.

Inactive Publication Date: 2007-12-26
SANJIAN PHARM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the oral chemically synthesized hypoglycemic drugs used in China mainly include yellow urea and biguanide, such as glyburide, Damekang, Mebida, Jiangtangling, etc. Traditional Chinese medicine prescriptions also contain the above two types of chemically synthesized hypoglycemic agents The ingredients of the medicine have positive hypoglycemic effect, but there are many side effects, and they have little effect on the prevention and treatment of chronic complications of diabetes, and the treatment of concurrent diseases is mainly symptomatic treatment. Same use, lack of left side, into square

Method used

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  • Composition of Chinese traditional medicine for treating diabetes, and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Example 1 Preparation of granules of the present invention

[0015] Take Rehmannia glutinosa 260g, red peony 260g, Coptis 50g, Ophiopogon 150g, mulberry leaf 150g, Pueraria lobata 150g, Polygonatum 150g, Danshen 240g, Huai Achyranthes 150g, Astragalus 240g, Epimedium 200g, cut into coarse grains, add 10 times the amount of water , Heating at 90 ℃, stirring and extracting for 2 hours, coarse filtration to separate the drug residue, high-speed centrifugation of the drug solution, filtration with a microporous membrane, and the filtrate is decompressed and concentrated to a clear ointment with a relative density of about 1.20 (60 ℃), with starch and paste The refined is an auxiliary material, and the weight ratio of the clear ointment to the auxiliary material is 2:1, and the spray-drying is completed at one time through a boiling fluidized bed to make 1000g.

Embodiment 2

[0016] Example 2 Preparation of capsules of the present invention

[0017] Take 400g of Rehmannia glutinosa, 170g of red peony root, 50g of coptis, 140g of Ophiopogon japonicus, 140g of mulberry leaf, 140g of kudzu root, 140g of rhizome of rhizome, 240g of salvia, 240g of huai achyranthes, 240g of astragalus, 200g of epimedium, cut into coarse grains and add 8 times the amount of water. Heating at 80°C, continuously stirring and extracting for 2 hours, coarse filtration to separate the drug residue, high-speed centrifugation of the drug solution, microporous filter membrane filtration, the filtrate is decompressed and concentrated to a clear ointment with a relative density of about 1.05 (60°C), and spray drying is completed at one time. Get it in capsules.

Embodiment 3

[0018] Example 3 Preparation of tablets of the invention

[0019] Take 210g of Rehmannia glutinosa, 160g of red peony root, 50g of coptis, 140g of Ophiopogon japonicus, 140g of mulberry leaf, 140g of kudzu root, 140g of rhizome, 240g of salvia, 240g of huai achyranthes, 240g of astragalus, 400g of epimedium, cut into coarse grains and add 12 times the amount of water. Heating at 60°C, stirring and extracting for 2 hours, coarse filtration to separate the dregs, high-speed centrifugation of the drug solution, filtration with a microporous membrane, the filtrate under reduced pressure and concentrated liquid to a clear ointment with a relative density of about 1.30 (60°C), and spray drying is completed at one time. Get it when pressed.

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Abstract

The present invention relates to a Chinese medicine composition for effectively curing diabetes. Said Chinese medicine composition contains 11 Chinese medicinal materials of rehmannia root, red peony root, coptis root, ophiopogon tuber, mulberry leaf, salvia root and others. Said Chinese medicine composition can be made into tablet preparation, capsule preparation, granules preparation and oral liquor, etc.

Description

Technical field [0001] The invention relates to a Chinese medicine composition, in particular to a Chinese medicine composition for treating diabetes and a preparation method thereof. Background technique [0002] Diabetes is a common endocrine and metabolic disease. In recent years, the number of diabetic patients in China has been increasing year by year. The incidence of urban residents exceeds 1%. Cardiovascular diseases include hypertensive heart disease, coronary atherosclerotic heart disease, and cerebrovascular diseases. One of the most serious complications is also the main cause of death of diabetes (about 70-90%). These complications are all related to blood stasis. At present, the oral chemically synthesized hypoglycemic agents used in China mainly include xanthan urea and biguanide, such as glyphosate, Damekang, Mebida, Jiangtangling, etc. The prescriptions of Chinese medicine also contain the above two types of chemically synthesized hypoglycemic agents The ingredie...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61K9/08A61K9/10A61K9/16A61K9/20A61K9/48A61P3/10
Inventor 周亚仙
Owner SANJIAN PHARM
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