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Sargentgloryvine tetraterpenes macrolide sodium complex agent for injections for treating knub and method for preparing the same

A technology for injections and injections, which is applied to medical preparations containing active ingredients, antitumor drugs, drug combinations, etc., can solve the problems of unguaranteed curative effect, changes in ingredients, and reproducibility of drugs that affect the stability of preparations. Achieve the effect of enhancing anti-cancer ability, promoting cell function, blocking tumor cell growth and metabolism

Inactive Publication Date: 2008-01-02
韦建学 +1
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  • Summary
  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

The traditional technology of traditional Chinese medicine injections is water boiling and alcohol precipitation, terminal sterilization, which is easy to cause composition changes, affect the stability of the preparation and the reproducibility of the drug, and the curative effect cannot be guaranteed

Method used

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  • Sargentgloryvine tetraterpenes macrolide sodium complex agent for injections for treating knub and method for preparing the same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0035] Embodiment: prepare medicine as follows:

[0036] (1). First infiltrate bamboo yellow with a dry weight of 5kg and epimedium with 5kg at 60°C respectively, then crush the cells through a colloid mill, so that the cells of bamboo yellow fungus and epimedium plant cells are completely broken; soak in water at 85°C Extract twice, each time for 2-3 hours, let stand for 30 minutes to denature the protein, combine the water extracts, naturally cool to room temperature and concentrate to a relative density of 1.0, and the concentrated solution is centrifuged at 4°C at a high speed (rotating speed 3500rpm, time 15 Minutes), the centrifuge discards the residue, retains the supernatant, and after the supernatant is separated by the acoustic membrane separator with the patent No. ZL03262745.9 developed by the designer, the separation liquid with a molecular weight less than 10000D is obtained;

[0037] (2). Dissolve 50 g of red rattan tetraterpene macrolide sodium in water for inj...

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Abstract

The invention discloses argentgloryvine tetraterpenes sodium large-ring lactone and the preparing method, which takes argentgloryvine tetraterpenes sodium large-ring lactone, tabasheer and barren wort as main raw material. The method comprises following steps: cell disintegrating, extracting with water soluble solution, freezing and centrifuging at low temperature, matching according to certain proportion based on different features of raw material, membrane separating, loading into intravenous drip injection (water injection, freeze dried, or large fluid infusion). The invention is characterized by special formulation and production process, separate utilization to treat tumor and cancer (mainly including gastric cancer, intestinal cancer, liver cancer, adenocarcinoma, lung carcinoma, uterocarcinoma, ovary cancer and breast cancer, etc. ), it can reduce the tumor size, induce cancer cell to die and kill cancer cell directly, increase cell metabolism, the effect is distinctive and no side effect. It a small amount of chemotherapy product is matched with medicine in this invention, the effect can be improved and shortens treatment period.

Description

technical field [0001] The invention belongs to the technical field of medicine preparation, and relates to a medicine preparation which is made from natural Chinese herbal medicine and can be widely used in various tumor treatments and a preparation method thereof. Background technique [0002] Tumors and cancers are comprehensive systemic dysfunction diseases, which are diseases of a new type of cell tissue formed due to the redifferentiation or mutation of the human body's own tissue cells. The metabolic activity of tumor cells is not required for human health. It has the characteristics of unfixed tissue shape and non-patterned metabolic activities. Tumor cells can transfer between tissues of the body and enter other tissues, eventually resulting in the metabolism of cells in normal tissues of the body. suffocated until exhaustion and death. For patients with advanced tumors, due to tumor enlargement or tumor metastasis, the patients suffer from abnormal pain, which ser...

Claims

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Application Information

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IPC IPC(8): A61K36/296A61K9/19A61P35/00A61K31/365
Inventor 韦建学王玲
Owner 韦建学
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