Di'ao Xinxuekang sustained-release preparation and its preparation method and use

Abstract

The invention provides a Di'ao Xinxuekang sustained-release preparation, which is composed of steroidal total saponins extracted from the rhizome of Chinese yam or / and Dioscorea punctatus as active ingredients, combined with solid dispersion technology and melting granulation technology or slow-release coating technology , that is, firstly mix the total steroidal saponins with a hydrophilic carrier material or / and a solubilizer to prepare a solid dispersion with excellent solubility, and then add a slow-release material to prepare the preparation. In vitro tests show that the sustained-release preparation is released continuously and smoothly within 24 hours, which provides a new option for the prevention and treatment of cardiovascular and cerebrovascular diseases.

Description

technical field

[0001] The invention relates to a slow-release preparation of traditional Chinese medicine, in particular to a slow-release preparation of Di'ao Xinxuekang and its preparation method and application. Background technique

[0002] Coronary heart disease and angina pectoris refer to the clinical syndrome caused by insufficient coronary blood supply, myocardial ischemia and hypoxia. "Heartache" and other syndrome categories. According to traditional Chinese medicine, the syndrome of thoracic obstruction is always a syndrome of deficiency in origin and excess in superficiality. Paralyzed. The cause of blocked heart vessels is of course due to blood stasis, phlegm turbidity, and stagnation of qi, and the occurrence of stasis, phlegm, and stagnation of qi is the result of long-term dysfunction of the viscera. Loss-based. Cardiac blockage, blockage leads to pain, chest pain attack or discomfort in the heart and chest; blood stasis blocks the collaterals, and the...

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