Application of hippophae rhamnoides fruit oil in the preparation of promoting mankind spermatozoon generation and both sexes aphoria medicine

A technology of seabuckthorn fruit oil and sperm production, which is applied in the field of pharmaceutical application of plant extracts, can solve the problems of few reports, and achieve the effect of preventing atrophy and improving sexual function

Inactive Publication Date: 2008-04-09
曾智
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  • Abstract
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AI Technical Summary

Problems solved by technology

However, there are few reports on the drugs that can really prove that there are drugs that can promote spermatogenesis in terms of morphology.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0008] In this experiment, 27 old male SD rats (30 months old) and 8 young rats (4 months old) were used. Randomly grouped into aging blank group, methyl testis group, calcium gluconate group, sea buckthorn fruit oil group, blank young group. It is formulated into equal dissolution liquid, and under the same environment, the test animals are respectively given appropriate medicines of 1.5-8 g / kg. Human test 1.5-8g / 70kg. The details are omitted.

[0009] The following experiment uses sea buckthorn whole fruit oil, rat, 3 g / kg.

[0010] Pharmacodynamic morphology results

[0011] 1. Testis and epididymal tissue morphology test

[0012] (Note: The following groups A, B, and D all have photos of the testis and epididymis tissue structure of old male rats (30 months old); Group C has photos of the testis and epididymis tissue structure of young male rats (4 months old); E The group has photos of the testis and epididymis tissue structure of the old male rats in the seabuckthorn whole-f...

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PUM

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Abstract

The invention relates to an application of seabuckthorn fruit oil and/or whole fruit oil in preparing medicine promoting the formation of male sperms, preventing the apoptosis of spermatogenic cells or promoting the formation of female ovarian follicles and the maturation of germ cells and treating male and female sterility. By taking the preparation, kidney deficiency and infirmity and various chronic diseases can be recovered to the health status, more effectively, the invention has the functions of promoting the formation of the male sperms and protecting the quantity of the spermatogenic cells, and preventing the apoptosis of spermatogenic cells, and can obviously increase the quantity and the motor ability of the sperms, and increase the weight of spermary, and simultaneously has the functions of promoting the formation of the female ovarian follicles and the maturation of the germ cells, thereby being used as the medicine for the clinical treatment of male and female sterility. Compared with other medicines, the medicine has simple ingredients, belongs to target organ excitant, and has the reversible automatic regulation function of a second messenger, thereby being the medicine with high curative effect, security, and simplification.

Description

Technical field [0001] The invention belongs to the medicinal application of plant extracts and is used for regulating male and female reproductive dysfunction. It can not only promote male sperm production, prevent male spermatogenic cells from shrinking and apoptosis, but also promote female follicle formation and promote egg maturation. It can be used to treat male and female infertility. Background technique [0002] With the progress and development of society, the proportion of male infertility in the population is gradually increasing. According to a report in the Chinese Journal of Andrology in December 2003, the proportion of male infertility may be higher than 12-16% in the future. The increase in the proportion of fertility indicates that male reproductive ability has declined, which is directly related to competition in the social environment (psychological pressure), environmental pollution, and personal habits (less sleep, smoking, excessive drinking, and less exerc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61P15/08A61K131/00
Inventor 魏霞蓁
Owner 曾智
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