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Yolk antibody feed additive and injection for resisting sheep virosis and preparation thereof

A viral disease and feed additive technology, applied in the field of feed and medicine, can solve the problems of unreported preparation methods, achieve high promotion and application value, alleviate clinical symptoms, and be easy to use

Inactive Publication Date: 2008-09-10
TIANJIN SHENGJI GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no report about the preparation method of yolk antibody against sheep infectious pustule, sheep bluetongue and sheep foot-and-mouth disease

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] An anti-goat viral disease egg yolk antibody feed additive is characterized in that it is a single vaccine prepared from sheep pustule virus, sheep bluetongue virus, sheep foot-and-mouth disease virus, or sheep pustule virus and / or sheep bluetongue virus and / or or sheep foot-and-mouth disease virus-prepared combined vaccine to immunize non-immune laying hens, and then collect egg yolks from the immune laying hens, extract and prepare them.

[0023] Preparation method of anti-sheep pustule virus, sheep bluetongue virus and sheep foot-and-mouth disease virus egg yolk antibody feed additive:

[0024] (1) Isolating sheep impetigo virus and / or sheep bluetongue disease virus and / or sheep foot-and-mouth disease virus for propagation and culture, and preparing a triple vaccine of sheep impetigo virus, sheep bluetongue disease virus and sheep foot-and-mouth disease virus after being antigenic.

[0025] (2) Utilize the prepared sheep pustule virus, sheep bluetongue virus and shee...

Embodiment 2

[0028] An anti-goat viral disease egg yolk antibody injection, characterized in that it is a single vaccine prepared from sheep impetigo virus, sheep bluetongue virus, sheep foot-and-mouth disease virus, or sheep impetigo virus and / or sheep bluetongue virus and / or The combined vaccine prepared by sheep foot-and-mouth disease virus is used to immunize non-immune laying hens, and then the egg yolk of the immune laying hens is collected, extracted and prepared.

[0029] The preparation method of anti-sheep pustus virus and sheep bluetongue virus egg yolk antibody injection:

[0030](1) Isolate the ovine impetigo virus and / or ovine bluetongue virus for propagation and culture, and prepare an ovine impetigo virus and ovine bluetongue virus dual vaccine when it has antigenicity.

[0031] (2) immunize non-immune laying hens with the prepared sheep pustule virus and sheep bluetongue virus dual vaccine, the immunization dose is 1.0ml during the first round of immunization injection; ca...

Embodiment 3

[0035] Preparation method of anti-sheep pustular virus, sheep bluetongue virus and sheep foot-and-mouth disease virus egg yolk antibody injection:

[0036] (1) Isolating sheep impetigo virus and / or sheep bluetongue disease virus and / or sheep foot-and-mouth disease virus for propagation and culture, and preparing a triple vaccine of sheep impetigo virus, sheep bluetongue disease virus and sheep foot-and-mouth disease virus after being antigenic.

[0037] (2) Utilize the prepared sheep pustule virus, sheep bluetongue virus and sheep foot-and-mouth disease virus triple vaccine to immunize non-immune laying hens, and the immune dose is 1.0ml during the first round of immunization injection; the second round is carried out 10 days later Immunization injection, the immunization dose is 2 times of the first immunization; after another 10 days, the third round of immunization injection is carried out, and the immunization dose is 4 times of the first immunization dose; after that, immu...

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PUM

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Abstract

The invention discloses an anti-sheep virus disease yolk antibody feed additive, an injection and a preparation method thereof. The anti-sheep virus disease yolk antibody feed additive and the injection respectively are extracted and prepared by the collected yolk antibody of the immunized laying hens which are immunized by the single vaccine which is prepared form sheep pustule virus, sheep bluetongue disease virus and sheep foot and mouth disease virus or the combined vaccine which is prepared from sheep pustule virus and / or sheep bluetongue disease virus and / or sheep foot and mouth disease virus. The anti-sheep virus disease yolk antibody prevents virus diseases through improving the antibody level of sheep antibodies on corresponding pathogen microorganisms causing the virus diseases. The feed additive of the invention is convenient to be fed to sheep with obvious control effect. The anti-sheep virus disease egg yolk antibody injection is provided with faster efficacy in the onset of the sheep. The anti-sheep virus disease yolk antibody feed additive, the injection and the preparing method thereof has the advantages of obvious efficacy, low cost, fast effect, no side effects, no drug-resistant strain which can be produced, simple preparation, wide raw material resource, convenient use and easy application.

Description

technical field [0001] The invention belongs to the field of feed and medicine, and in particular relates to an anti-goat viral disease egg yolk antibody feed additive and injection and a preparation method. Background technique [0002] Sheep contagious impetigo is a contagious disease of sheep caused by impetigo virus, also known as sheep sore. The disease occurs all over the world, and it occurs wherever there are sheep. The harm to adult sheep is mild, but the harm to lambs is serious, the mortality rate is between 1% and 15%, and the recovery and development are hindered. Sick sheep and infected sheep are the source of infection of the disease. Healthy sheep are mainly transmitted through contact. Infected pens, forage grass, utensils, etc. can be indirectly infected, mostly in groups. As long as one sheep becomes ill, it will quickly spread to the whole group. In the case of lack of forage, thin sheep, lack of milk for lambs, and reduced disease resistance, it is ea...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K39/42A61K9/08A23K1/00C07K16/08A61P31/12A23K20/10
Inventor 古长庆
Owner TIANJIN SHENGJI GRP CO LTD
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