Extracting method of valerine

Abstract

The invention discloses a valerianine distillation method. After being ground, the valerianine is degreased through aether which is a solvent with low boiling point; after that the valerianine is marinated in t chloroform methanol mixture for distillation; the target product valerianine A is produced through dilute hydrochloric acid extraction process, together with silica gel and alumina column chromatographic separation process and recrystalization process. The purity of the valerianine A reaches 98%, satisfying requirements to medical materials. Valerianine is a natural quaternary ammoniumalkaloid and has antidepressant function and sedative, hypnotic and anti-convulsion effects.

Description

technical field

[0001] The invention relates to a method for extracting natural quaternary ammonium alkaloids, which are N-p-hydroxyphenethyl derivatives of actinidine, and are one of the main effective components of valerian root for antidepressant, sedative, hypnotic and anticonvulsant effects. Background technique

[0002] With the development of society, the acceleration of the pace of life, and the intensification of competition, people's mental stress is also gradually increasing. More and more people are paying attention to drugs that can relieve mental tension, regulate qi and calm the nerves, and promote sleep. However, most of the commodities with similar effects sold on the market are synthesized by chemical methods. After taking it, it will cause obvious side effects and discomfort symptoms to the nervous system, and produce drug dependence. Therefore, the market is in urgent need of a drug or health food that is safe and effective, has no side effects, can help...

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