Medicament for treating gynaecologic urinary system infection contamination and preparation method thereof

A technology for urinary system infections and drugs, applied in the fields of urinary system diseases, drug combinations, pharmaceutical formulas, etc.

Active Publication Date: 2008-12-03
北京羚锐伟业科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] To sum up, most of the traditional Chinese medicines currently on the market for treating gynecological urinary tract infections are medicines for clearing away heat and promoting dampness. The dialectic is damp-heat in the lower jiao, and the medicines for those with insufficient spleen and kidney are still rare

Method used

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  • Medicament for treating gynaecologic urinary system infection contamination and preparation method thereof
  • Medicament for treating gynaecologic urinary system infection contamination and preparation method thereof
  • Medicament for treating gynaecologic urinary system infection contamination and preparation method thereof

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Effect test

Embodiment 1

[0026] Embodiment 1, the present invention treats the preparation of gynecological urinary system infection medicine

[0027] Drugs for the treatment of gynecological urinary system infection, the traditional Chinese medicine prescription is as follows: Cortex Phellodendri 225g, Shiwei 450g, Rhizome Imperatae 300g, Atractylodes Rhizome 150g, Poria cocos 225g, Alisma 180g, Dipsacus 180g, Lycium barbarum 180g, Cortex Moutan 150g, Dandelion 225g, Burnet 180g, talcum powder 270g, licorice 45g.

[0028] The method for preparing the medicine for treating gynecological urinary system infection comprises the following specific steps:

[0029] 1) Weigh the medicinal materials according to the components and their weights in the above-mentioned traditional Chinese medicine prescription, and perform routine pretreatment;

[0030]2) Crush Phellodendron Phellodendri into coarse powder, add ethanol and reflux 3 times, each time for 1 hour, combine the ethanol solution, recover ethanol unde...

Embodiment 2

[0037] Embodiment 2, the experiment of the influence of the medicine of the present invention for the treatment of gynecological urinary system infection on guinea pig Steblay type interstitial nephritis animal model

[0038] Adopt the medicine for the treatment of gynecological urinary system infection prepared in embodiment 1 (clinical experiment tentatively named as Niaoshuang capsule), carry out animal experiment to Steblay type interstitial nephritis model guinea pig, by control experiment, investigate medicine of the present invention to Steblay type interstitial nephritis model guinea pig Protective effect in guinea pigs model of chronic nephritis. The specific experimental process is as follows:

[0039] (1) Take guinea pigs: 430-460g, 40 males, and divide them randomly into 5 groups, namely ①normal control group, ②model blank group, ③positive control group, ④Niaoshuang capsule low-dose group, ⑤Niaoshuang capsule high dose group.

[0040] (2) method:

[0041] A. Pre...

Embodiment 3

[0054] Embodiment 3, the present invention treats the bacteriostatic experiment of the medicine of gynecological urinary system infection in vitro

[0055] Adopt the medicine for the treatment of gynecological urinary system infection prepared in embodiment 1 (clinical experiment tentatively named as Niaoshuang capsule), to the MIC and MBC of Escherichia coli, Proteus, Staphylococcus aureus, Streptococcus Bacillus standard strain and clinical strain in vitro , through a control experiment, investigate the effect of the medicine of the present invention on bacteria in vitro. The specific experimental process is as follows:

[0056] (1) Experimental materials:

[0057] A. Preparation of Niaoshuang Capsule Extract: Add 1.0g of the patented medicine to 10ml with distilled water, put it in a water bath at 37°C and shake for 24 hours to filter it, take the filtrate and add distilled water to 10ml so that the concentration of the medicine is 10% (patented medicine), autoclave After...

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Abstract

The invention relates to a medicine for treating gynaecological urinary system infection. The medicine is prepared by the following raw materials by weight portion: 1.30 to 1.70 portions of phellodendron, 2.80 to 3.20 portions of folium pyrrosiae, 1.80 to 3.20 portions of cogongrass rhizome, 1 grams of atractylis ovata, 1.30 to 1.70 portions of poria cocos, 1.00 to 1.40 portions of alisma orientale, 1.00 to 1.40 portions of teasel roots, 1.00 to 1.40 portions of Chinese wolfberry fruit, 0.80 to 1.20 portions of tree peony root barks, 1.30 to 1.70 grams of dandelion, 1.00 to 1.40 portions of sanguisorba, 1.60 to 2.00 portions of talcum powder and 0.10 to 0.50 portion of liquorice. The invention also discloses a method for producing the medicine for treating the gynaecological urinary system infection. The medicine reduces fever and promotes urination, and invigorates the spleen and strengthens the kidney, and is used for diseases such as urgent micturition, frequent micturition, urination fever, odynuria, lumbago, hypogastric pain and so on caused by damp heat retention. Compared with the prior art, the healing effect is more obvious, and the functions of the medicine are obviously superior to those of Sanjin tablets.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a medicine for treating gynecological urinary system infection and a preparation method thereof. Background technique [0002] Urinary tract infection is the most common infectious disease, especially women after the age of 35 often relapse. About 20-50% of women will have at least one urinary tract infection in their lifetime. The disease is easy to recur. Someone followed 100 cases of female pyelonephritis for 10 to 20 years, and 41% of the patients relapsed within three years. Due to multiple treatments, multiple attacks caused a vicious circle, which became chronic and unhealed. With the continuous development and improvement of national health care, the majority of patients have higher and higher requirements and hopes for the quality, variety, curative effect and physical health care of drugs, especially the clinical research of some difficult diseases, which h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K9/48A61P13/02A61P13/10A61K33/12
Inventor 张军兵武惠斌余家相
Owner 北京羚锐伟业科技有限公司
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