Medicament for treating gynaecologic urinary system infection contamination and preparation method thereof
A urinary system infection and drug technology, applied in the direction of urinary system diseases, drug combination, medical formula, etc., to achieve the effects of obvious formula characteristics, improved curative effect, and peaceful medication
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Embodiment 1
[0026] Embodiment 1, the present invention treats the preparation of gynecological urinary system infection medicine
[0027] Drugs for the treatment of gynecological urinary system infection, the traditional Chinese medicine prescription is as follows: Cortex Phellodendri 225g, Shiwei 450g, Rhizome Imperatae 300g, Atractylodes Rhizome 150g, Poria cocos 225g, Alisma 180g, Dipsacus 180g, Lycium barbarum 180g, Cortex Moutan 150g, Dandelion 225g, Burnet 180g, talcum powder 270g, licorice 45g.
[0028] The method for preparing the medicine for treating gynecological urinary system infection comprises the following specific steps:
[0029] 1) Weigh the medicinal materials according to the components and their weights in the above-mentioned traditional Chinese medicine prescription, and perform routine pretreatment;
[0030]2) Crush Phellodendron Phellodendri into coarse powder, add ethanol and reflux 3 times, each time for 1 hour, combine the ethanol solution, recover ethanol unde...
Embodiment 2
[0037] Embodiment 2, the experiment of the influence of the medicine of the present invention for the treatment of gynecological urinary system infection on guinea pig Steblay type interstitial nephritis animal model
[0038] Adopt the medicine for the treatment of gynecological urinary system infection prepared in embodiment 1 (clinical experiment tentatively named as Niaoshuang capsule), carry out animal experiment to Steblay type interstitial nephritis model guinea pig, by control experiment, investigate medicine of the present invention to Steblay type interstitial nephritis model guinea pig Protective effect in guinea pigs model of chronic nephritis. The specific experimental process is as follows:
[0039] (1) Take guinea pigs: 430-460g, 40 males, and divide them into 5 groups at random, namely ①normal control group, ②model blank group, ③positive control group, ④Niaoshuang capsule low-dose group, ⑤Niaoshuang capsule high dose group.
[0040] (2) method:
[0041] A. Pr...
Embodiment 3
[0054] Embodiment 3, the present invention treats the bacteriostatic experiment of the medicine of gynecological urinary system infection in vitro
[0055] Adopt the medicine for the treatment of gynecological urinary system infection prepared in embodiment 1 (clinical experiment tentatively named as Niaoshuang capsule), to the MIC and MBC of Escherichia coli, Proteus, Staphylococcus aureus, Streptococcus Bacillus standard strain and clinical strain in vitro , through a control experiment, investigate the effect of the medicine of the present invention on bacteria in vitro. The specific experimental process is as follows:
[0056] (1) Experimental materials:
[0057] A. Preparation of Niaoshuang Capsule Extract: Add 1.0g of the patented medicine to 10ml with distilled water, put it in a water bath at 37°C and shake for 24 hours to filter it, take the filtrate and add distilled water to 10ml so that the concentration of the medicine is 10% (patented medicine), autoclave After...
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