Process for preparing capsule for urinary system lithiasis

A technique for urinary calculus and its production method, which is applied in the fields of urinary system diseases, capsule delivery, medical preparations containing active ingredients, etc. It can solve the problems of low content of active substances, single effect of western medicine, and many additives in tablets, etc., to achieve Easy to take, unique curative effect, good stability

Inactive Publication Date: 2008-12-10
LUOYANG ZISHENG TECH DEV
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AI Technical Summary

Problems solved by technology

[0002] At present, there are many Chinese patent medicines commonly used in the clinical treatment of urinary calculus diseases, each of which has its own characteristics, and all of them have quite good effects; however, the drugs for treating urinary calculi are mainly western medicines, and the effects of western medicines are often too single
Someone once designed to make Chinese medicinal materials such as red peony root and Smilax tuckahoe into tablets, and the auxiliary materials are soluble starch, talcum powder, and magnesium stearate. However, this product has poor stability and is easy to absorb moisture and deteriorate. The content of substances is low and the dosage is large

Method used

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Embodiment Construction

[0010] Desmodium 15g, Gallinarum 0.3g, Akebia 0.3g, Qumai 0.3g, Plantago 0.3g, Talc 0.5g, Licorice 0.4g, Amber powder 0.1g. Crush into fine powder and pass through a 100-mesh sieve. A total of 1720g medicinal materials, decocted twice with water, firstly added 13.76kg of water for 1.5 hours, added 13.76kg of water for the second time and decocted for 1.5 hours, combined the filtrate, filtered, and the filtrate was concentrated to a relative density of 1.10( 70 DEG C) clear ointment, spray drying, drying temperature is about 120 DEG C, make dry ointment powder, mix with above-mentioned fine powder, get dry medicinal powder. Calculation of one medium and two components: Weigh 500g of dry medicine powder and 25g of magnesium stearate according to the ratio of 1:0.05, mix them evenly, use 4ml of edible ethanol concentrated to 70% as a wetting agent to make wet granules, and dry them at about 50°C. Make 1000 capsules, pass the inspection, and powdery, promptly get the finished pro...

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Abstract

The present invention discloses a manufacturing method for a capsule which is applicable to the urinary stone. In the present invention, nine medicinal materials comprising desmodium, chicken gizzard membrane, akebia stem, twotoothed achyranthes root, lilac pink, Asiatic plantain seed, talcum, licorice root tip and amber powder are finely finished and made into dry medical powder which is mixed with magnesium stearate in proportion to be made into wet granules with ethanol as a humectant, and the wet granules are dried and filled into a capsule to obtain the capsule. The medicine of the present invention has simple and clear structure, advanced technology, easily controlled quality, high technical content, good taste and good stability, is convenient for the patient to take and does not absorb water easily; the capsule has the characteristics of high biological utilization degree and same curative effect as other preparation formulations. The preparation has reasonable design, is convenient for taking and carrying and has unique curative effect for the urinary stone.

Description

technical field [0001] The invention relates to a medicine suitable for urinary stone capsules. In particular, it is a method for making capsules of nine traditional Chinese medicinal materials such as Desmodium chinensis, Gallus japonicus, Akebia, etc., for treating urinary stones. Background technique [0002] At present, there are many Chinese patent medicines commonly used in the clinical treatment of urinary calculus diseases, each of which has its own characteristics, and all of them have quite good effects; however, the drugs for treating urinary calculus are mainly western medicines, and the effects of western medicines are often too single. Someone once designed to make Chinese medicinal materials such as red peony root and Smilax tuckahoe into tablets, and the auxiliary materials are soluble starch, talcum powder, and magnesium stearate. However, this product has poor stability and is easy to absorb moisture and deteriorate. The substance content is low, and the d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/68A61K36/8964A61K9/48A61P13/04A61K35/38A61K35/10A61K33/12A61K33/06A61K35/57
Inventor 王忠东
Owner LUOYANG ZISHENG TECH DEV
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