Secondary fermentation method natural medicinal preparation, preparation and use

A secondary fermentation method, a technology of natural medicines, applied in the field of multi-component natural medicine preparations, can solve problems such as the unreported process of natural antibacterial medicine preparations, and achieve significant social benefits.

Active Publication Date: 2008-12-17
周应揆
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Using traditional Chinese medicine as raw material, the process of natural antibacterial drug preparation obtained through secondary fermentation engineering has not been reported

Method used

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  • Secondary fermentation method natural medicinal preparation, preparation and use
  • Secondary fermentation method natural medicinal preparation, preparation and use
  • Secondary fermentation method natural medicinal preparation, preparation and use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Strain preparation: The production strain is Ganoderma lucidum (Leyss.ex Fr.)

[0026] Traits: Ganoderma lucidum commonly referred to refers to the fruit body of Ganoderma lucidum. In the present invention, the mycelium of Ganoderma lucidum is mainly used as a strain for fermentation. Mycelium culture characteristics and microscopic examination: The strains are inoculated on the potato culture slant, the temperature is 24-26℃, and the cultivation time is 120 hours to grow colorless or nearly white flocculent mycelium, or do a single plate colony culture, colony Irregular, colorless or nearly white flocculent mycelium, with radial edges.

[0027] Inoculate the above-mentioned strains in potato culture medium, culture at 24-35℃, shaker 180-220 times / min, pH value is natural, culture for 5-7 days, make bacterial suspension, as the first time and Strains for the second fermentation (bacteria suspension).

[0028] The first fermentation: Weigh 100g of gentian grass, mulberry bar...

Embodiment 2

[0031] Example 2: The four fermentation broths were mixed in a ratio of 1:3:3:1, propylene glycol used 10%; purified water used 70%, and the others were the same as in Example 1, and will not be repeated.

Embodiment 3

[0032] Example 3: Four fermentation broths were mixed at a ratio of 1:2.2:2.2:1; propylene glycol was 8%; purified water was 73%. Others are the same as in Example 1, and will not be repeated.

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PUM

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Abstract

The invention relates to a multi-component natural pharmaceutical preparation which adopts traditional Chinese medicines as raw materials, is prepared by biological secondary fermentation engineering technology and biochemical technology and has high-efficient broad spectrum antibacterial activity, safe use and stable drug effect, that is, a natural antibacterial drug obtained by fermentation engineering. The pharmaceutical preparation adopts Chinese medicines as raw materials; ganoderma lucidum is fermented, in the process of fermentation, fermented mesostate with high antibacterial activity and biological activity is obtained by the secondary fermentation process and suspending the secondary fermentation process in the mid course, in the manner, a stock solution preparation which can resist HIV, various venereal pathogens and bird flu virus is obtained, the stock solution preparation is mixed with other components to produce the high-efficient natural antibacterial pharmaceutical preparation with broad spectrum. The pharmaceutical preparation is characterized by no toxic and side effect, nonirritant and no allergic reaction and safe and reliable use, which can be applied to medicines for treating and preventing various venereal pathogenic bacteria, bird flu virus and various antiseptic hygienic products such as an ultrasonic atomization agent, a detergent, an air-conditioning freshener and wet wipe for medical use.

Description

Technical field: [0001] The invention relates to a multi-component natural drug preparation with high-efficiency broad-spectrum antibacterial activity, safe use, and stable efficacy, prepared by biological secondary fermentation engineering technology and biochemical technology using traditional Chinese medicines as raw materials, that is, natural medicines obtained through fermentation engineering. Antibacterial drugs. Background technique: [0002] The development status and trends at home and abroad in the relevant technical fields have entered the 21st century. Traditional medicine has once again radiated strong vitality in the world trend of "returning to nature", presenting broad prospects for modern development, and combining it with modern medical technology. The key to entering the international market. Using traditional Chinese medicine as raw material, the natural antibacterial preparation process obtained by secondary fermentation process has not been reported. Summa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/605A61P31/00A61P31/22A61P33/02A61P15/02A01N63/02C11D3/48C11D9/50A61L9/013
Inventor 周应揆周石蒙周诺
Owner 周应揆
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