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Traditional Chinese medicine composition for treating hyperlipemia, preparation and quality control method thereof

A quality control method and technology for hyperlipidemia, applied in the direction of drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve the problem that the curative effect is difficult to reach the level of Western medicines for reducing blood lipids, there are many side effects, and patients are not suitable for long-term Taking and other issues

Active Publication Date: 2009-03-18
BEIJING ASIA EAST BIO PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, the medicine western medicines for the treatment of such diseases mainly include bile acid chelating resins, nicotinic acid, statins, clofibrates, etc., but there are many side effects, and patients should not take it for a long time. Then there are outstanding advantages, not only significant curative effect, but also long-term use without side effects, to achieve the purpose of treating both symptoms and root causes, but at present there are few traditional Chinese medicine preparations for treating hyperlipidemia, most of which are used to treat hyperlipidemia in addition to the effect of treating other diseases , its curative effect is difficult to reach the level of western medicine hypolipidemic drugs

Method used

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  • Traditional Chinese medicine composition for treating hyperlipemia, preparation and quality control method thereof
  • Traditional Chinese medicine composition for treating hyperlipemia, preparation and quality control method thereof
  • Traditional Chinese medicine composition for treating hyperlipemia, preparation and quality control method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0300] Example 1 Rumex 200-300 parts by weight Pueraria 120-250 parts by weight Lotus leaf 120-250 parts by weight

[0301] Salvia 120-250 parts by weight Rhubarb 90-170 parts by weight Cynomorium 90-170 parts by weight

[0302] Gynostemma 120~250 parts by weight

[0303] Collect rhubarb, Gynostemma, Salvia, Cynomorium and grind them into medium powder (65-85 mesh), add 6-10 times the amount of 80-90% ethanol to reflux extract 1-3 times, each time for 1-3 hours, combine The extract is filtered, and the ethanol is recovered from the filtrate under reduced pressure and concentrated into a clear paste with a relative density of 1.20-1.30 (50°C) for later use; the lotus leaf and kudzu root are crushed into coarse powder (30-60 mesh), and the above-mentioned medicinal residues are added, Mix, add 6-10 times the amount of water to decoct 1-3 times, 1-3 hours each time, combine the decoction, filter, combine the filtrate with the above clear paste, mix well, concentr...

Embodiment 2

[0304] Example 2 Rhubarb 200-300 parts by weight, Gynostemma 120-250 parts by weight, Nankudingcha 120-250 parts by weight, lotus leaf 120-250 parts by weight, Polygonum cuspidatum 70-150 parts by weight, Red ginseng 120-250 parts by weight 90-170 parts by weight of rhubarb, 90-170 parts by weight of cistanche

[0305] Take soil Rhubarb, Gynostemma, Polygonum cuspidatum, and Cistanche, and grind them into medium powder (65-85 mesh), add 6-10 times the amount of 80-90% ethanol to reflux and extract 1-3 times, each time for 1-3 hours, and extract together liquid, filtered, and the filtrate was decompressed to recover ethanol and concentrated into a clear paste with a relative density of 1.20-1.30 (50°C) for later use; the lotus leaf and nankuding tea were crushed into coarse powder (30-60 mesh), and the above-mentioned medicine Dregs, mix, add 6-10 times the amount of water and decoct 1-3 times, 1-3 hours each time, combine the decoction, filter, combine the filtrate with the ab...

Embodiment 3

[0306] Example 3 Rhubarb 250g, Jiaogulan 150g, Nankudingcha 150g, lotus leaf 150g, Polygonum cuspidatum 90g, red ginseng 150g, rhubarb 100g, Cistanche 100g

[0307] The above eight medicinal materials, rhubarb, Gynostemma, Polygonum cuspidatum, and Cistanche are respectively crushed into medium powder (65-85 mesh), and 8 times the amount of 85% ethanol is refluxed for 2 hours for the first time, and 6 times the amount of 85% ethanol is added for the second time. % ethanol reflux extraction for 2 hours, combined extracts, filtered, filtrate decompression recovery ethanol and concentrated into a relative density of 1.20 ~ 1.30 (50 ℃) clear paste, standby; lotus leaf, nankudingcha pulverized into coarse powder ( 30-60 mesh), add the above dregs, mix, add water to decoct, add 8 times the amount of water to decoct for 2 hours for the first time, add 6 times the amount of water to decoct for 1 hour for the second time, combine the decoction, filter, The filtrate is combined with the...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for treating hyperlipemia, a preparation method and a quality control method thereof. The traditional Chinese medicine composition is made from the crude drugs such as rumex madaio makino, fiveleaf gynostemma herb, south broadleaf holly leaf, lotus leaf, giant knotweed, Yunnan madder root, rhubarb, broomrape and the like; in the quality control method of the composition, high performance liquid chromatography is adopted to determine the content of emodin, and the rumex madaio makino, the fiveleaf gynostemma herb, the giant knotweed and the broomrape are subject to qualitative thin layer identification. The composition has better drug effect, and has remarkable curative effects on the hyperlipermia resulting from phlegm stasis with symptoms of dizziness, chest stuffiness, fatness, constipation, etc.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating hyperlipidemia and its preparation method and quality control method, in particular to a preparation method and quality of a traditional Chinese medicine composition tablet for hyperlipidemia caused by phlegm turbidity and blood stasis The control method belongs to the technical field of traditional Chinese medicine. Background technique [0002] The damage of hyperlipidemia to the body is hidden, gradual, progressive and systemic. Its direct damage is to accelerate systemic atherosclerosis, because vital organs of the whole body rely on arterial blood supply and oxygen supply. Once the arteries are blocked by atherosclerotic plaques, serious consequences will result. Renal failure caused by arteriosclerosis is closely related to hyperlipidemia. A large number of research data show that hyperlipidemia is an independent and important risk factor for stroke, coronary heart...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/708A61K9/16A61K9/20A61K9/48G01N30/02G01N30/90A61P3/06
Inventor 付立家付建家
Owner BEIJING ASIA EAST BIO PHARMA CO LTD
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