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Use of traditional Chinese medicine in preparing medicine for treating retinal vein obstruction

A technology of retinal veins and compositions, which is applied in the direction of drug combinations, active ingredients of hydroxyl compounds, and medical raw materials derived from arthropods, etc. The effect of blood viscosity

Inactive Publication Date: 2009-03-25
HEBEI YILING MEDICINE INST
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The above two patents do not disclose the application of the traditional Chinese medicine composition in the treatment of retinal vein occlusion

Method used

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  • Use of traditional Chinese medicine in preparing medicine for treating retinal vein obstruction

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Experimental program
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Effect test

Embodiment 1

[0049] a) The raw material drug formula is:

[0050] Ginseng 39.6g Leech 72.6g Wood Beetle 46.2g Frankincense (made) 13.2g

[0051] Paeoniae Rubra 33g Dalbergia 13.2g Sandalwood 13.2g Scorpio 19.8g

[0052] Cicada slough 46.2g centipede 6.6g borneol 33g Suanzaoren (stir-fried) 33g;

[0053] b) Crushing process of medicinal materials:

[0054] The scorpion, leech, centipede, ground beetle, and cicada slough five kinds of insect medicines have been cleaned, washed and processed, and the frankincense prepared after cleaning is prepared according to the prescription, and crushed by a pulverizer, and the fineness of the powder reaches more than 80 mesh; The powdered medicine is ultrafinely pulverized by various ultrafine pulverization techniques, so that the average particle size of the medicine powder is less than 30-40 μm; the medicinal materials to be pulverized are washed, dried and sterilized, and the ingredients are prepared;

[0055] c) Extraction concentration and drying...

experiment example

[0062] 1 Materials and methods

[0063] 1.1 General information

[0064] 52 routines (72 eyes) are clinically diagnosed as RVO patients and are completely randomly divided into two groups, the drug group of the present invention (observation group), 27 examples of 37 eyes, 14 males (20 eyes), 13 females (17 eyes); There were 7 cases (10 eyes) of central vein obstruction, including 2 cases of ischemic type and 5 cases of non-ischemic type; 20 cases (27 eyes) of branch vein obstruction, including 6 cases of ischemic type and 14 cases of non-ischemic type; age 23 to 68 years old, with an average age of 55.5±9.7 years; the course of disease ranged from 3 to 90 days, with an average of 31.9±23.8 days. Danshen injection group (control group) (manufactured by Shijiazhuang Shineway Pharmaceutical Co., Ltd.) 25 cases (35 eyes), 13 males (19 eyes), 12 females (16 eyes), including 8 cases (9 eyes) of retinal vein central trunk obstruction , including 3 cases of ischemic type and 6 case...

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Abstract

The invention discloses a traditional Chinese medicine composite which is applied to preparing the medicine for curing retinal vein occlusion. The traditional chinese medicine composite is composed of ginseng, leech, centipede, scorpion, woodlouse, cicada slough, red peony root and borneol and the like, with efficiency of supplementing qi and activating blood circulation and eliminating blood stasis and freeing channels. The traditional chinese medicine composite has the function of osmosis resistance, strengthening the venous constriction, improving the flexibility of the vein wall, and increasing the venous pressure of the blood vessel wall, so as to reach the detumescence and relief purpose for vein blood stasis symptom, alleviate retinal edema and the edema in blood vessels, strengthen retinal artery blood supplying and improve the sight of patients who have retinal vein occlusion. The traditional chinese medicine composite has obvious curative effects on curing the retinal vein occlusion, and the total curative effect ratio which is validated in clinical trials of curing the retinal vein occlusion through the traditional chinese medicine composite can reach 91.9%, with security and simplicity and few adverse effects.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition. Specifically, the invention relates to an application of a traditional Chinese medicine composition in preparing a medicine for treating retinal vein occlusion, which belongs to the field of traditional Chinese medicine application. Background technique [0002] Retinal vein occlusion (RVO) is a blinding retinal disease characterized by tortuous and dilated retinal veins and retinal hemorrhage, edema, and exudation in the drainage area of ​​the affected veins. Its clinical manifestations are: vision loss, optic nerve head hyperemia, edema, blurred border, retinal edema, centripetal, flame-like, linear superficial retinal hemorrhage, punctate and patchy hemorrhage; retinal veins dilated to varying degrees, Distortion, reflexive narrowing of the retinal artery; edema and hard exudation may appear in the macula, and cotton wool spots may also appear in the posterior ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61P27/02A61K31/045A61K35/62A61K35/64A61K35/646A61K35/648
Inventor 李向军安军永李云鹏
Owner HEBEI YILING MEDICINE INST
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