Folium ginkgo extract micropill and preparation method thereof
An extract and technology of ginkgo biloba, applied in the field of pellets made of ginkgo biloba extract and its preparation, can solve the problems of long disintegration time, low bioavailability, irritation of gastric mucosa, etc., and achieve good effectiveness, High bioavailability, total dose reduction effect
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[0033] Example 1
[0034] Take the ingredients of the following formula for use
[0035] Ginkgo biloba extract 10g Microcrystalline cellulose 85g Hydroxypropylmethylcellulose 5g
[0036] Prepare the pellet preparation according to the following method:
[0037] (1) Take the ginkgo biloba extract of the above formula and add the microcrystalline cellulose, pulverize it to the micronization level with a ball mill, and mix;
[0038] (2) Dissolve hydroxypropyl methylcellulose in 75% ethanol solution;
[0039] (3) Pellets are made by extrusion-spheronization method.
Example Embodiment
[0040] Example 2
[0041] Take the ingredients of the following formula for use
[0042] Ginkgo biloba extract 40g sucrose 55g Polyvinylpyrrolidone 5g
[0043] Prepare the pellet preparation according to the following method:
[0044] (1) Take the ginkgo biloba extract of the above formula and add sucrose, pulverize it to the micronized level with a ball mill, and mix;
[0045] (2) Dissolve polyvinylpyrrolidone in water;
[0046] (3) Pellets are made by pan-pill method.
Example Embodiment
[0047] Example 3
[0048] Take the ingredients of the following formula for use
[0049] Ginkgo biloba extract 60g sucrose 25g starch 11g Polyvinylpyrrolidone 4g
[0050] Prepare the pellet preparation according to the following method:
[0051] (1) Take the ginkgo biloba extract of the above formula, add sucrose and starch, pulverize it to a micronized level with a ball mill, and mix;
[0052] (2) Dissolve polyvinylpyrrolidone in water;
[0053] (3) Using centrifugal-fluidized pelletizing method to make pellets.
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