Traditional Chinese compound for curing central obesity and nonalcoholic fatty liver disease and preparation method thereof

A non-alcoholic and fatty liver technology, applied in the field of traditional Chinese medicine compound for treating central obesity and non-alcoholic fatty liver and its preparation field, can solve the problem of increasing the risk of cardiovascular death, restricting the application of lipid-lowering drugs, and increasing blood lactic acid. It can improve the CT ratio of liver and spleen, improve the fibrinolysis-coagulation function, and reduce the level of liver transaminase.

Inactive Publication Date: 2009-09-16
王文健
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Problems solved by technology

Metformin can increase blood lactic acid levels; rosiglitazone itself can increase body weight, and has adverse reactions such as headache and edema, and has recently been reported to increase the risk of cardiovascular death
Fatty liver patients are often accompanied by hyperlipidemia, a...

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  • Traditional Chinese compound for curing central obesity and nonalcoholic fatty liver disease and preparation method thereof
  • Traditional Chinese compound for curing central obesity and nonalcoholic fatty liver disease and preparation method thereof

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Embodiment Construction

[0020] A traditional Chinese medicine for treating central obesity and non-alcoholic fatty liver, characterized in that the traditional Chinese medicine is composed of astragalus, coptis, rhubarb, raw puhuang, and capillary, wherein astragalus, coptis, rhubarb, raw puhuang, and capillary The weight ratio is: 1~4:1:1~3:1~3:1~3. According to a preferred embodiment of the present invention, the weight ratio of Radix Astragali, Coptidis Rhizome, Radix Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizome 1.5-3:1:1-2:1-2:1-2 is 1.5-3:1:1-2:1-2. Alisma and / or raw hawthorn can also be added to the traditional Chinese medicine, wherein the weight ratio of Alisma and coptis is 0.7-1.2:1, and the weight ratio of raw hawthorn and coptis is 1-2:1.

[0021] After the traditional Chinese medicine is mixed with water and extracted, the traditional Chinese medicine compound preparation ca...

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Abstract

The invention discloses a traditional Chinese compound preparation for curing nonalcoholic fatty liver and central obesity and is characterized in that the compound preparation is prepared by adding medicinal excipient to the extractives of milk veteh, rhizoma coptidis, prepared rhubarb, raw cattail pollen and herba artemisiae capillaris, wherein the weight mixture ratio of milk veteh, rhizoma coptidis, prepared rhubarb, raw cattail pollen and herba artemisiae capillaris is 1-4:1:1-3:1-3:1-3. Proved by clinical trial, the drug combination of the invention can reduce the abdominal perimeter of patients, lower the AUC (area under curve) of triglyceride after dinner, improve the CT specific value of liver and spleen and bring down the transaminase level of liver with evident treatment effect. Verified by clinical research, the compound can obviously increase the insulin sensitivity of patients, lower inflammatory factor level and improve fibrinolysis-blood clotting function. Shown by experimental research, the drug of the invention can enhance the sensitivity of fat and muscle cells to insulin and has significant value in treating nonalcoholic fatty liver and central obesity which take insulin resistance as fundamental pathological link.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine compound for treating central obesity and non-alcoholic fatty liver and a preparation method thereof. Background technique [0002] According to the working definition of metabolic syndrome by the International Diabetes Federation (IDF), central obesity is a prerequisite for determining metabolic syndrome and is the most intuitive external sign of insulin resistance. The standard of Chinese central obesity defined by IDF is that the abdominal circumference of men is greater than 90cm, and the abdominal circumference of women is greater than 80cm; and according to the "Guidelines for the Control of Overweight and Obesity in Chinese Adults (Trial)" issued by the Department of Disease Control of the Ministry of Health in 2003 , the standard of central obesity for Chinese people is ≥85cm for men and ≥80cm for women. [0003] Non-alcoholic f...

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Application Information

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IPC IPC(8): A61K36/88A61K36/884A61P3/04A61P1/16
Inventor 王文健
Owner 王文健
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