Interface device for coupling capillary electrophoresis with inductively coupled plasma mass spectrograph and use method thereof
A technology of capillary electrophoresis and inductive coupling, which is applied in the field of chemical analysis, can solve the problems of unable to provide very stable electrical connection, unable to solve the problem of peak broadening, and no commercial interface, etc., to achieve fast measurement speed, high sensitivity, and improved sensitivity. Effect
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Example Embodiment
[0011] Example 1
[0012] When the sample is separated in the capillary electrophoresis instrument, the current controller controls the rotation of the cleaning solution peristaltic pump 4 and stops the sample solution peristaltic pump 5, which will not affect the separation of the capillary electrophoresis instrument; when a certain component in the sample is separated, The current controller controls the cleaning solution peristaltic pump 4 to stop, and rotates the sample solution peristaltic pump 5 to send the components to be measured into the inductively coupled plasma mass spectrometer for measurement. Since the peristaltic pump 4 has stopped and no auxiliary liquid enters, the inductively coupled plasma mass spectrometer The sensitivity of the instrument is not affected. The detection limits of different substance concentrations in the collection and injection mode are shown in Table 1.
[0013] Table 1
[0014] Analyte
Example Embodiment
[0015] Example 2
[0016] When the sample is separated in the capillary electrophoresis apparatus, the current controller controls the cleaning solution peristaltic pump 4 and the sample solution peristaltic pump 5 to rotate at different speeds at the same time. When a certain component in the sample separates and flows out of the capillary, it is immediately sent into the inductively coupled plasma Mass spectrometry is used for the determination, the determination speed is very fast and the dead volume is small, so as to realize continuous sampling. The detection limits of different substance concentrations in continuous injection mode are shown in Table 2.
[0017] Table 2
[0018]
[0019] The pump speeds of Examples 1 and 2 are shown in Table 3 below:
[0020] table 3
[0021]
[0022] The speed of pump 5 is basically fixed at 12μL / min, and the speed of pump 4 is related to the nature of the object to be tested. It must be adjusted according to the nature o...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap