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Chinese medicinal composition for preventing and treating Mycoplasma gallisepticum and preparation method thereof

A technology of Mycoplasma gallisepticum and a composition, which is applied in directions such as drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, can solve problems such as blank liquid preparations, achieve difficult drug residues, reduce air sac damage rates, and reduce air sacs. The effect of drug resistance

Inactive Publication Date: 2010-05-12
NORTHEAST AGRICULTURAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the dosage forms of Chinese herbal medicines for this disease are mainly powders, and the liquid preparations are temporarily blank.

Method used

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  • Chinese medicinal composition for preventing and treating Mycoplasma gallisepticum and preparation method thereof
  • Chinese medicinal composition for preventing and treating Mycoplasma gallisepticum and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] (1) Weigh each raw material according to the following weight (unit: g): 200 scutellaria, 200 honeysuckle, 200 aster, 200 ephedra, 100 tangerine peel, 100 licorice;

[0041](2) Decoct honeysuckle, aster, ephedra, tangerine peel and licorice with water twice, add 10 times the weight of water and decoct for 2 hours for the first time, add honeysuckle after 1 hour of decoction, add 10 times the weight of water for the second time and decoct Boil for 1.5h, filter, and combine the filtrates. Concentrate the filtrate to about 4 times the weight of the crude drug, add ethanol with a final concentration of 65%, let it rest, and keep it overnight at 4°C. Filter to remove the precipitate, concentrate the filtrate until there is no alcohol smell, cool, add ethanol with a final concentration of 75%, and keep overnight at 4°C. Filter to remove the precipitate, and the filtrate is concentrated to a crude drug content of 1 g / mL, and set aside. Decoct Scutellaria baicalensis pieces w...

Embodiment 2

[0043] (1) Weigh each raw material according to the following weight (unit: g): 100 scutellaria baicalensis, 100 honeysuckle, 100 aster, 100 ephedra, 20 tangerine peel, 20 licorice;

[0044] (2) Decoct honeysuckle, aster, ephedra, tangerine peel and licorice with water twice, add 10 times the weight of water and decoct for 2 hours for the first time, add honeysuckle after 1 hour of decoction, add 10 times the weight of water for the second time and decoct Boil for 1.5h, filter, and combine the filtrates. Concentrate the filtrate to about 4 times the weight of the crude drug, add ethanol with a final concentration of 65%, let it rest, and keep it overnight at 4°C. Filter to remove the precipitate, concentrate the filtrate until there is no alcohol smell, cool, add ethanol with a final concentration of 75%, and keep overnight at 4°C. Filter to remove the precipitate, and the filtrate is concentrated to a crude drug content of 1 g / mL, and set aside. Decoct Scutellaria baicalens...

Embodiment 3

[0046] (1) Weigh each raw material according to the following weight (unit: g): 400 scutellaria, 400 honeysuckle, 400 aster, 400 ephedra, 150 tangerine peel, 150 licorice;

[0047] (2) Decoct honeysuckle, aster, ephedra, tangerine peel and licorice with water twice, add 10 times the weight of water and decoct for 2 hours for the first time, add honeysuckle after 1 hour of decoction, add 10 times the weight of water for the second time and decoct Boil for 1.5h, filter, and combine the filtrates. Concentrate the filtrate to about 4 times the weight of the crude drug, add ethanol with a final concentration of 65%, let it rest, and keep it overnight at 4°C. Filter to remove the precipitate, concentrate the filtrate until there is no alcohol smell, cool, add ethanol with a final concentration of 75%, and keep overnight at 4°C. Filter to remove the precipitate, and the filtrate is concentrated to a crude drug content of 1 g / mL, and set aside. Decoct Scutellaria baicalensis pieces ...

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Abstract

The invention discloses a Chinese medicinal composition for preventing and treating Mycoplasma gallisepticum and a preparation method thereof. The Chinese medicinal composition is prepared from the following raw material medicaments in part by weight: 1 to 4 parts of baical skullcap root, 1 to 4 parts of honeysuckle, 1 to 4 parts of tatarian aster root, 1 to 4 parts of ephedra herb, 0.2 to 1.5 parts of tangerine peel and 0.2 to 1.5 parts of liquoric root. The Chinese medicinal composition has the effects of clearing heat and releasing toxin, moistening the lung to stop cough, relieving cough and removing asthma, eliminating inflammation and relieving pain, improving immunity and the like, has simple preparation process, low cost, no toxic or side effect, and is not easy to generate medicament resistance. Various active components in the oral liquid of the Chinese medicinal composition are dispersed in a medium in a molecule or microparticle state, have high dispersity, are quickly absorbed, and can quickly begin to work. Clinical pharmacodynamic experiment results show that the Chinese medicinal composition has good treatment effect on chronic respiratory disease and the like caused by the Mycoplasma gallisepticum infection, and can also improve the weight increment of chickens and fodder returns.

Description

technical field [0001] The invention relates to a veterinary traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for preventing and treating mycoplasma gallisepticum, belonging to the field of traditional Chinese veterinary medicine. Background technique [0002] Mycoplasma gallisepticum (MG) often causes chronic respiratory disease in chickens, which is a highly contagious chronic infectious disease, clinically characterized by abnormal breath sounds, cough, runny nose, and dyspnea. The clinical course of the disease is chronic, and the course of the disease is long, and it is often mixed with other pathogens, resulting in aggravated respiratory symptoms and increased mortality; and because the growth and development of infected chickens are hindered, the discarded rate of carcass defective products is increased, and the egg production rate is reduced. pose a serious threat to the poultry industry. Primary disease all can t...

Claims

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Application Information

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IPC IPC(8): A61K36/752A61P31/00A61P11/00
Inventor 李继昌盛尊来姜晓文潘晓影陈春丽石乔尹建华
Owner NORTHEAST AGRICULTURAL UNIVERSITY
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