Traditional Chinese medicine preparation for preventing influenza

Abstract

The invention provides a traditional Chinese medicine for preventing influenza. The traditional Chinese medicine comprises crude drugs such as folium isatidis, subprostrate sophora, herba elsholtziae, aleppo avens, platycodon grandiflorum, abrus cantoniensis hance, artemisia apiacea, ginseng leaves, radix angelicae, rhizoma anemarrhenae, manyleaf paris rhizome, burdock, cloves, groundsel, lalang grass rhizome, rhizoma dryopteris crassirhizomae, rheum officinale, radix bupleuri, Chinese barberry roots, semen sojae germinatum, Chinese yams, lonicerae flos, concretio silicea bambusae, rainbow conk, ligusticum and herba epimedii. The traditional Chinese medicine for preventing the influenza can inhibit virus replication, adjust the immune function and realize a broad-spectrum antibacterial effect, has a good effect on prevention of the influenza, is not prone to development of drug resistance and free from toxic and side effects and adverse reactions and can adjust the immune functions of human bodies well.

Description

technical field

[0001] The invention relates to the field of epidemic prevention medicine, in particular to a traditional Chinese medicine preparation for preventing influenza. Background technique

[0002] Influenza (flu for short) is a highly contagious acute respiratory disease caused by influenza virus. Influenza is very harmful to human health, mainly manifested in its frequent epidemics, rapid spread, general susceptibility of the population, large number of patients, etc., and it can cause serious complications. Therefore, the prevention and control of influenza is very important.

[0003] Influenza vaccination is currently the most effective measure to prevent influenza. Whole-virus vaccines have good effectiveness and safety, and the effective rate of vaccination can reach 60% to 90%. The immune response after subunit vaccination is weaker than that of whole-virus vaccines; cross-immunity to different influenza viruses can be obtained by inoculating live vaccines ...

Examples

preparation example Construction

[0065] Preferably, the present invention also provides the preparation method of above-mentioned Chinese medicine, when the dosage form of described Chinese medicine is granule, concrete steps are:

[0066] The first step is to mix Folium Folium Folium, Blue Buzheng, Chicken Bone Grass, Ginseng Leaf, Burdock Fructus, Soybean Yellow Roll, Chinese Yam and Epimedium in proportion, and add 15 to 25 times the mass of the mixture with an alcohol concentration of 75% to 85% % ethanol, stir evenly, seal and soak for 4 to 6 days to obtain soaking liquid, soaking liquid percolates through the percolation tank, the flow rate is 3 to 5ml per minute, collect the percolating liquid, filter, and the filtrate is at -0.09 to -0.06MPa , Under the condition of 50-70°C, the solvent is recovered, and vacuum concentrated into an extract with a relative density of 1.15-1.20;

[0067] The second step is to absorb the macroporous resin on the extract, the mass ratio of the mass of the extract to the m...

Embodiment 1

[0077] Embodiment 1 Granule 1

[0078] Mix 80g of Folium Folium Folium, 55g of Blue Cloth, 40g of Chickweed, 50g of Ginseng Leaf, 30g of Burdock Fructus, 25g of Soybean Yellow Roll, 40g of Chinese Yam and 40g of Epimedium, add 7.2kg of ethanol with an alcohol concentration of 80%, and stir Evenly, sealed and soaked for 6 days to obtain the soaking solution, the soaking solution was percolated through the percolation tank, the flow rate was 3ml per minute, the percolation solution was collected, filtered, and the filtrate was recovered from the solvent at -0.07MPa and 60°C, and concentrated in vacuo to For the extract with a relative density of 1.15, absorb the D101 macroporous resin on the extract, the mass ratio of the extract to the macroporous adsorption resin is 3:1, first wash it with water until the effluent is colorless, and then use the relative macropore adsorption The quality 6 times of the resin is eluted with ethanol with an alcohol concentration of 80%, and the el...

Embodiment 2

[0079] Embodiment 2 Granules 2

[0080] Mix 75g of Folium Folium Folium, 50g of blue cloth, 35g of chicken bone grass, 45g of ginseng leaves, 35g of arctium, 30g of soybean yellow rolls, 45g of yam and 45g of epimedium, add 7.2kg of ethanol with an alcohol concentration of 80%, and stir Evenly, sealed and soaked for 6 days to obtain the soaking solution, the soaking solution was percolated through the percolation tank, the flow rate was 3ml per minute, the percolation solution was collected, filtered, and the filtrate was recovered from the solvent at -0.07MPa and 60°C, and concentrated in vacuo to For the extract with a relative density of 1.15, absorb the D101 macroporous resin on the extract, the mass ratio of the extract to the macroporous adsorption resin is 3:1, first wash it with water until the effluent is colorless, and then use the relative macropore adsorption The quality 6 times of the resin is eluted with ethanol with an alcohol concentration of 80%, and the eluen...

technical field

[0001] The invention relates to the field of epidemic prevention medicine, in particular to a traditional Chinese medicine preparation for preventing influenza. Background technique

[0002] Influenza (flu for short) is a highly contagious acute respiratory disease caused by influenza virus. Influenza is very harmful to human health, mainly manifested in its frequent epidemics, rapid spread, general susceptibility of the population, large number of patients, etc., and it can cause serious complications. Therefore, the prevention and control of influenza is very important.

[0003] Influenza vaccination is currently the most effective measure to prevent influenza. Whole-virus vaccines have good effectiveness and safety, and the effective rate of vaccination can reach 60% to 90%. The immune response after subunit vaccination is weaker than that of whole-virus vaccines; cross-immunity to different influenza viruses can be obtained by inoculating live vaccines ...

Examples

preparation example Construction

[0065] Preferably, the present invention also provides the preparation method of above-mentioned Chinese medicine, when the dosage form of described Chinese medicine is granule, concrete steps are:

[0066] The first step is to mix Folium Folium Folium, Blue Buzheng, Chicken Bone Grass, Ginseng Leaf, Burdock Fructus, Soybean Yellow Roll, Chinese Yam and Epimedium in proportion, and add 15 to 25 times the mass of the mixture with an alcohol concentration of 75% to 85% % ethanol, stir evenly, seal and soak for 4 to 6 days to obtain soaking liquid, soaking liquid percolates through the percolation tank, the flow rate is 3 to 5ml per minute, collect the percolating liquid, filter, and the filtrate is at -0.09 to -0.06MPa , Under the condition of 50-70°C, the solvent is recovered, and vacuum concentrated into an extract with a relative density of 1.15-1.20;

[0067] The second step is to absorb the macroporous resin on the extract, the mass ratio of the mass of the extract to the m...

Embodiment 1

[0077] Embodiment 1 Granule 1

[0078] Mix 80g of Folium Folium Folium, 55g of Blue Cloth, 40g of Chickweed, 50g of Ginseng Leaf, 30g of Burdock Fructus, 25g of Soybean Yellow Roll, 40g of Chinese Yam and 40g of Epimedium, add 7.2kg of ethanol with an alcohol concentration of 80%, and stir Evenly, sealed and soaked for 6 days to obtain the soaking solution, the soaking solution was percolated through the percolation tank, the flow rate was 3ml per minute, the percolation solution was collected, filtered, and the filtrate was recovered from the solvent at -0.07MPa and 60°C, and concentrated in vacuo to For the extract with a relative density of 1.15, absorb the D101 macroporous resin on the extract, the mass ratio of the extract to the macroporous adsorption resin is 3:1, first wash it with water until the effluent is colorless, and then use the relative macropore adsorption The quality 6 times of the resin is eluted with ethanol with an alcohol concentration of 80%, and the el...

Embodiment 2

[0079] Embodiment 2 Granules 2

[0080] Mix 75g of Folium Folium Folium, 50g of blue cloth, 35g of chicken bone grass, 45g of ginseng leaves, 35g of arctium, 30g of soybean yellow rolls, 45g of yam and 45g of epimedium, add 7.2kg of ethanol with an alcohol concentration of 80%, and stir Evenly, sealed and soaked for 6 days to obtain the soaking solution, the soaking solution was percolated through the percolation tank, the flow rate was 3ml per minute, the percolation solution was collected, filtered, and the filtrate was recovered from the solvent at -0.07MPa and 60°C, and concentrated in vacuo to For the extract with a relative density of 1.15, absorb the D101 macroporous resin on the extract, the mass ratio of the extract to the macroporous adsorption resin is 3:1, first wash it with water until the effluent is colorless, and then use the relative macropore adsorption The quality 6 times of the resin is eluted with ethanol with an alcohol concentration of 80%, and the eluen...

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