Application of actinidine for preparing medicament for treating atherosclerosis
A technology for atherosclerosis and actinidine, which is applied in drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., and can solve problems such as the disclosure of the application of actinidine in atherosclerosis drugs.
Active Publication Date: 2010-06-30
江苏芝能生物科技有限公司
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Problems solved by technology
[0009] In the prior art, there is no disclosure of the application of actinidinine as a drug for the preparation of atherosclerosis
Method used
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Embodiment 1
[0044] Tablet: Actinidinine 25g, starch 175g, granulated, compressed into 1000 tablets. Dosage: Adults take 1 tablet at a time, 2 times a day.
Embodiment 2
[0046] Capsules: 25g of actinine, 175g of microcrystalline cellulose, mixed well, made into 1000 capsules. Dosage: Adults take 1 capsule at a time, 2 times a day.
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The invention relates to an application method of actinidine for preparing a medicament for treating atherosclerosis. By using the actinidine to prepare the medicament for treating atherosclerotic, the prepared medicament can obviously reduce the blood fat, raise the NO content in the sera, decrease the ET-1 content and inhibit the development of plaques, and the effects are remarkable.
Description
technical field [0001] The present invention relates to the application method of actinidine, especially the application method in the preparation of medicine for treating atherosclerosis. Background technique [0002] Actinidine is a natural compound with molecular formula: C10H13N and molecular weight: 147.219. Actinidinine exists widely in various plants of Actinidiaceae, and in natural products, it generally exists in the (S)-form. The CAS accession number of (S)-type actinidinine: 524-03-8, the structural formula is as follows: [0003] [0004] Kiwi fruit is the fruit of Actinidia chinensis Planch. [0005] Atherosclerosis (AS) is the most common and important type of arteriosclerosis; it is the arterial wall cells, extracellular matrix, blood components (especially monocytes, platelets, and low-density lipoproteins), local blood flow It is the result of the comprehensive action of many factors such as dynamics, environment and genetics; it is the pathological ba...
Claims
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IPC IPC(8): A61K31/438A61P9/10
Inventor 王琳范淦彬
Owner 江苏芝能生物科技有限公司
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